Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial

|Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to r...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2014-01, Vol.2014 (2014), p.1-12
Hauptverfasser: Su, Min, Feng, Ping, Chen, Jing, Qin, Peipei, Ren, Li, Peng, Lihua, Lin, Haidan
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container_end_page 12
container_issue 2014
container_start_page 1
container_title Evidence-based complementary and alternative medicine
container_volume 2014
creator Su, Min
Feng, Ping
Chen, Jing
Qin, Peipei
Ren, Li
Peng, Lihua
Lin, Haidan
description |Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P < 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P < 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.
doi_str_mv 10.1155/2014/569107
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To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P &lt; 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P &lt; 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2014/569107</identifier><identifier>PMID: 25254055</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Analgesia ; Analgesics ; Anesthesia ; Clinical trials ; Comparative analysis ; Evidence-based medicine ; Femur ; Incidence ; Intravenous administration ; Joint surgery ; Knee ; Methods ; Nerve block ; Nonsteroidal anti-inflammatory drugs ; Osteoarthritis ; Pain ; Pain perception ; Patients ; Rehabilitation ; Salvage ; Surgeons ; Surgery</subject><ispartof>Evidence-based complementary and alternative medicine, 2014-01, Vol.2014 (2014), p.1-12</ispartof><rights>Copyright © 2014 Lihua Peng et al.</rights><rights>COPYRIGHT 2014 John Wiley &amp; Sons, Inc.</rights><rights>Copyright © 2014 Lihua Peng et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2014 Lihua Peng et al. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c553t-d1dee7bda8cb97277bf372ab481a3fc6940f219b8c188295cf1a232375732b943</citedby><cites>FETCH-LOGICAL-c553t-d1dee7bda8cb97277bf372ab481a3fc6940f219b8c188295cf1a232375732b943</cites><orcidid>0000-0002-5202-910X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164420/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164420/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25254055$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Yu, Huang-Ping</contributor><creatorcontrib>Su, Min</creatorcontrib><creatorcontrib>Feng, Ping</creatorcontrib><creatorcontrib>Chen, Jing</creatorcontrib><creatorcontrib>Qin, Peipei</creatorcontrib><creatorcontrib>Ren, Li</creatorcontrib><creatorcontrib>Peng, Lihua</creatorcontrib><creatorcontrib>Lin, Haidan</creatorcontrib><title>Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>|Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P &lt; 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P &lt; 0.001 and P = 0.031 , resp.). Conclusion. 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To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P &lt; 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P &lt; 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>25254055</pmid><doi>10.1155/2014/569107</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-5202-910X</orcidid><oa>free_for_read</oa></addata></record>
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subjects Analgesia
Analgesics
Anesthesia
Clinical trials
Comparative analysis
Evidence-based medicine
Femur
Incidence
Intravenous administration
Joint surgery
Knee
Methods
Nerve block
Nonsteroidal anti-inflammatory drugs
Osteoarthritis
Pain
Pain perception
Patients
Rehabilitation
Salvage
Surgeons
Surgery
title Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial
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