Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial
|Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to r...
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description | |Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P < 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P < 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia. |
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fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4164420</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A417106315</galeid><sourcerecordid>A417106315</sourcerecordid><originalsourceid>FETCH-LOGICAL-c553t-d1dee7bda8cb97277bf372ab481a3fc6940f219b8c188295cf1a232375732b943</originalsourceid><addsrcrecordid>eNqNkk2P0zAQhiMEYpeFE3dkiQsClbWdOHb2gFQqFlaUD1VF4mY5zqTrxbGLnQYtf46_hrMtpXAByZItzTPveGbeLHtI8HNCGDulmBSnrKwI5reyY8ILMimoELf3b_75KLsX4xXGtOKc382OKKOswIwdZz9m3vXGbfwmonPofFAWvYcwAHppvf6CBggxhS5cH9QAbsQ-qt6A69GYGby10KCpU3YF0SjU-oDeOgD0ztfGmv4aKdeguXeryRJCl5KNQ-nsRCJagAYzGLdCS9-n4jfJC1hbpaFLxBmaokXS8J35niodFF0Go-z97E6rbIQHu_sk-3T-ajl7M5l_eH0xm84nmrG8nzSkAeB1o4SuK045r9ucU1UXgqi81WVV4JaSqhaaCEErpluiaE5zznhO66rIT7IXW931pu6g0TAOxMp1MJ0K19IrI_-MOHMpV36QBSmLguIk8GQnEPzXDcRediZqsFY5SFOVhJeCiZxX_N8oK8u07JyN6OO_0Cu_CWkbUVJcUoGJKNlvaqUsSONan76oR1E5LQgnuMzJSD3bUjr4GAO0--4IlqPT5Og0uXVaoh8dDmTP_rJWAp5ugUvjGvXN_J8aJARadQDfdJD_BM135oI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2062801865</pqid></control><display><type>article</type><title>Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial</title><source>Wiley Online Library Open Access</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>PubMed Central Open Access</source><creator>Su, Min ; Feng, Ping ; Chen, Jing ; Qin, Peipei ; Ren, Li ; Peng, Lihua ; Lin, Haidan</creator><contributor>Yu, Huang-Ping</contributor><creatorcontrib>Su, Min ; Feng, Ping ; Chen, Jing ; Qin, Peipei ; Ren, Li ; Peng, Lihua ; Lin, Haidan ; Yu, Huang-Ping</creatorcontrib><description>|Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P < 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P < 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2014/569107</identifier><identifier>PMID: 25254055</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Analgesia ; Analgesics ; Anesthesia ; Clinical trials ; Comparative analysis ; Evidence-based medicine ; Femur ; Incidence ; Intravenous administration ; Joint surgery ; Knee ; Methods ; Nerve block ; Nonsteroidal anti-inflammatory drugs ; Osteoarthritis ; Pain ; Pain perception ; Patients ; Rehabilitation ; Salvage ; Surgeons ; Surgery</subject><ispartof>Evidence-based complementary and alternative medicine, 2014-01, Vol.2014 (2014), p.1-12</ispartof><rights>Copyright © 2014 Lihua Peng et al.</rights><rights>COPYRIGHT 2014 John Wiley & Sons, Inc.</rights><rights>Copyright © 2014 Lihua Peng et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2014 Lihua Peng et al. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c553t-d1dee7bda8cb97277bf372ab481a3fc6940f219b8c188295cf1a232375732b943</citedby><cites>FETCH-LOGICAL-c553t-d1dee7bda8cb97277bf372ab481a3fc6940f219b8c188295cf1a232375732b943</cites><orcidid>0000-0002-5202-910X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164420/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164420/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25254055$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Yu, Huang-Ping</contributor><creatorcontrib>Su, Min</creatorcontrib><creatorcontrib>Feng, Ping</creatorcontrib><creatorcontrib>Chen, Jing</creatorcontrib><creatorcontrib>Qin, Peipei</creatorcontrib><creatorcontrib>Ren, Li</creatorcontrib><creatorcontrib>Peng, Lihua</creatorcontrib><creatorcontrib>Lin, Haidan</creatorcontrib><title>Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>|Objectives. To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P < 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P < 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.</description><subject>Analgesia</subject><subject>Analgesics</subject><subject>Anesthesia</subject><subject>Clinical trials</subject><subject>Comparative analysis</subject><subject>Evidence-based medicine</subject><subject>Femur</subject><subject>Incidence</subject><subject>Intravenous administration</subject><subject>Joint surgery</subject><subject>Knee</subject><subject>Methods</subject><subject>Nerve block</subject><subject>Nonsteroidal anti-inflammatory drugs</subject><subject>Osteoarthritis</subject><subject>Pain</subject><subject>Pain perception</subject><subject>Patients</subject><subject>Rehabilitation</subject><subject>Salvage</subject><subject>Surgeons</subject><subject>Surgery</subject><issn>1741-427X</issn><issn>1741-4288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk2P0zAQhiMEYpeFE3dkiQsClbWdOHb2gFQqFlaUD1VF4mY5zqTrxbGLnQYtf46_hrMtpXAByZItzTPveGbeLHtI8HNCGDulmBSnrKwI5reyY8ILMimoELf3b_75KLsX4xXGtOKc382OKKOswIwdZz9m3vXGbfwmonPofFAWvYcwAHppvf6CBggxhS5cH9QAbsQ-qt6A69GYGby10KCpU3YF0SjU-oDeOgD0ztfGmv4aKdeguXeryRJCl5KNQ-nsRCJagAYzGLdCS9-n4jfJC1hbpaFLxBmaokXS8J35niodFF0Go-z97E6rbIQHu_sk-3T-ajl7M5l_eH0xm84nmrG8nzSkAeB1o4SuK045r9ucU1UXgqi81WVV4JaSqhaaCEErpluiaE5zznhO66rIT7IXW931pu6g0TAOxMp1MJ0K19IrI_-MOHMpV36QBSmLguIk8GQnEPzXDcRediZqsFY5SFOVhJeCiZxX_N8oK8u07JyN6OO_0Cu_CWkbUVJcUoGJKNlvaqUsSONan76oR1E5LQgnuMzJSD3bUjr4GAO0--4IlqPT5Og0uXVaoh8dDmTP_rJWAp5ugUvjGvXN_J8aJARadQDfdJD_BM135oI</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Su, Min</creator><creator>Feng, Ping</creator><creator>Chen, Jing</creator><creator>Qin, Peipei</creator><creator>Ren, Li</creator><creator>Peng, Lihua</creator><creator>Lin, Haidan</creator><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QP</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-5202-910X</orcidid></search><sort><creationdate>20140101</creationdate><title>Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial</title><author>Su, Min ; 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To evaluate the comparative analgesia effectiveness and safety of postoperative continuous femoral nerve block (CFNB) with patient controlled intravenous analgesia (PCIA) and their impact on knee function and chronic postoperative pain. Methods. Participants were randomly allocated to receive postoperative continuous femoral nerve block (group CFNB) or intravenous patient controlled analgesia (group PCIA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for knee and incidence of chronic postoperative pain at 3, 6, and 12 months postoperatively were compared. postoperative pain and salvage medication at rest or during mobilization 24 hours, 48 hours, and 7 days postoperatively were also recorded. Results. After discharge from the hospital and rehabilitation of joint function, patients in group CFNB reported significantly improved knee flexion and less incidence of chronic postoperative pain at 3 months and 6 months postoperatively ( P < 0.05 ). Analgesic rescue medications were significantly reduced in patients receiving CFNB ( P < 0.001 and P = 0.031 , resp.). Conclusion. With standardized rehabilitation therapy, continuous femoral nerve block analgesia reduced the incidence of chronic postoperative pain, improved motility of replaced joints, and reduced the dosages of rescue analgesic medications, suggesting a recovery-enhancing effect of peripheral nerve block analgesia.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>25254055</pmid><doi>10.1155/2014/569107</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-5202-910X</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Analgesia Analgesics Anesthesia Clinical trials Comparative analysis Evidence-based medicine Femur Incidence Intravenous administration Joint surgery Knee Methods Nerve block Nonsteroidal anti-inflammatory drugs Osteoarthritis Pain Pain perception Patients Rehabilitation Salvage Surgeons Surgery |
title | Continuous Femoral Nerve Block versus Intravenous Patient Controlled Analgesia for Knee Mobility and Long-Term Pain in Patients Receiving Total Knee Replacement: A Randomized Controlled Trial |
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