Hypolipidemic and Antioxidant Activity of Enoki Mushrooms (Flammulina velutipes)
According to the literatures, Flammulina velutipes contains biologically active components such as dietary fiber, polysaccharide, and mycosterol, whose effects in reducing blood sugar, blood pressure, and cholesterol have been proven. This study used the active components extracted from Flammulina v...
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| description | According to the literatures, Flammulina velutipes contains biologically active components such as dietary fiber, polysaccharide, and mycosterol, whose effects in reducing blood sugar, blood pressure, and cholesterol have been proven. This study used the active components extracted from Flammulina velutipes powder (FVP) and Flammulina velutipes extract (FVE) to investigate the impact of these active components on lipid metabolism of hamsters. The results show that the total dietary fiber content in FVP and FVE is 29.34 mg/100 g and 15.08 mg/100 g, respectively. The total mycosterol content is 46.57 ± 0.37 mg/100 g and 9.01 ± 0.17 mg/100 g, respectively. The male hamsters were subjected to lipid metabolism monitoring by adding 1, 2, and 3% FVP or FVE into their diets for a period of 8 weeks. The animal assay results show that the 3% FVP and FVE groups have the lowest concentration of TC (total cholesterol), TG (triacylglycerol), LDL (low density lipoprotein cholesterol), and LDL/HDL (high density lipoprotein cholesterol) in the serum and liver (P < 0.05). Our results demonstrate that the addition of 3% FVP or FVE has a significant effect on the lipid metabolism in hamsters whose increased level of HDL in the serum was induced by high fat diet. |
| doi_str_mv | 10.1155/2014/352385 |
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This study used the active components extracted from Flammulina velutipes powder (FVP) and Flammulina velutipes extract (FVE) to investigate the impact of these active components on lipid metabolism of hamsters. The results show that the total dietary fiber content in FVP and FVE is 29.34 mg/100 g and 15.08 mg/100 g, respectively. The total mycosterol content is 46.57 ± 0.37 mg/100 g and 9.01 ± 0.17 mg/100 g, respectively. The male hamsters were subjected to lipid metabolism monitoring by adding 1, 2, and 3% FVP or FVE into their diets for a period of 8 weeks. The animal assay results show that the 3% FVP and FVE groups have the lowest concentration of TC (total cholesterol), TG (triacylglycerol), LDL (low density lipoprotein cholesterol), and LDL/HDL (high density lipoprotein cholesterol) in the serum and liver (P < 0.05). Our results demonstrate that the addition of 3% FVP or FVE has a significant effect on the lipid metabolism in hamsters whose increased level of HDL in the serum was induced by high fat diet.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2014/352385</identifier><identifier>PMID: 25250317</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Administration, Oral ; Animals ; Antioxidants ; Antioxidants - administration & dosage ; Biological activity ; Blood pressure ; Cardiovascular disease ; Cholesterol ; Chromatography ; Cricetinae ; Decomposition ; Dietary fiber ; Dietary Fiber - administration & dosage ; Flammulina - chemistry ; Flammulina velutipes ; Free radicals ; Fungal Polysaccharides - administration & dosage ; Hypolipidemic Agents - administration & dosage ; Lipid Metabolism - drug effects ; Lipid Metabolism - physiology ; Lipids ; Lipoproteins, HDL - blood ; Liver ; Male ; Mesocricetus ; Molecular weight ; Mushrooms ; Nutrition research ; Sterols - administration & dosage</subject><ispartof>BioMed research international, 2014-01, Vol.2014 (2014), p.1-6</ispartof><rights>Copyright © 2014 Ming-Yei Yeh et al.</rights><rights>COPYRIGHT 2014 John Wiley & Sons, Inc.</rights><rights>Copyright © 2014 Ming-Yei Yeh et al. Ming-Yei Yeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2014 Ming-Yei Yeh et al. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-3f4437581200ef4982434aab63af4f233358da9555d18d74df858431d57dd6c43</citedby><cites>FETCH-LOGICAL-c528t-3f4437581200ef4982434aab63af4f233358da9555d18d74df858431d57dd6c43</cites><orcidid>0000-0001-6290-2702</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164374/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164374/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25250317$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Weng, Chia-Jui</contributor><creatorcontrib>Yeh, Ming-Yei</creatorcontrib><creatorcontrib>Lin, Li-Yun</creatorcontrib><creatorcontrib>Ko, Wen-Ching</creatorcontrib><title>Hypolipidemic and Antioxidant Activity of Enoki Mushrooms (Flammulina velutipes)</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>According to the literatures, Flammulina velutipes contains biologically active components such as dietary fiber, polysaccharide, and mycosterol, whose effects in reducing blood sugar, blood pressure, and cholesterol have been proven. 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Our results demonstrate that the addition of 3% FVP or FVE has a significant effect on the lipid metabolism in hamsters whose increased level of HDL in the serum was induced by high fat diet.</description><subject>Administration, Oral</subject><subject>Animals</subject><subject>Antioxidants</subject><subject>Antioxidants - administration & dosage</subject><subject>Biological activity</subject><subject>Blood pressure</subject><subject>Cardiovascular disease</subject><subject>Cholesterol</subject><subject>Chromatography</subject><subject>Cricetinae</subject><subject>Decomposition</subject><subject>Dietary fiber</subject><subject>Dietary Fiber - administration & dosage</subject><subject>Flammulina - chemistry</subject><subject>Flammulina velutipes</subject><subject>Free radicals</subject><subject>Fungal Polysaccharides - administration & dosage</subject><subject>Hypolipidemic Agents - administration & dosage</subject><subject>Lipid Metabolism - drug effects</subject><subject>Lipid Metabolism - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BioMed research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yeh, Ming-Yei</au><au>Lin, Li-Yun</au><au>Ko, Wen-Ching</au><au>Weng, Chia-Jui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypolipidemic and Antioxidant Activity of Enoki Mushrooms (Flammulina velutipes)</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>2014</volume><issue>2014</issue><spage>1</spage><epage>6</epage><pages>1-6</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>According to the literatures, Flammulina velutipes contains biologically active components such as dietary fiber, polysaccharide, and mycosterol, whose effects in reducing blood sugar, blood pressure, and cholesterol have been proven. This study used the active components extracted from Flammulina velutipes powder (FVP) and Flammulina velutipes extract (FVE) to investigate the impact of these active components on lipid metabolism of hamsters. The results show that the total dietary fiber content in FVP and FVE is 29.34 mg/100 g and 15.08 mg/100 g, respectively. The total mycosterol content is 46.57 ± 0.37 mg/100 g and 9.01 ± 0.17 mg/100 g, respectively. The male hamsters were subjected to lipid metabolism monitoring by adding 1, 2, and 3% FVP or FVE into their diets for a period of 8 weeks. The animal assay results show that the 3% FVP and FVE groups have the lowest concentration of TC (total cholesterol), TG (triacylglycerol), LDL (low density lipoprotein cholesterol), and LDL/HDL (high density lipoprotein cholesterol) in the serum and liver (P < 0.05). Our results demonstrate that the addition of 3% FVP or FVE has a significant effect on the lipid metabolism in hamsters whose increased level of HDL in the serum was induced by high fat diet.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>25250317</pmid><doi>10.1155/2014/352385</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-6290-2702</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Administration, Oral Animals Antioxidants Antioxidants - administration & dosage Biological activity Blood pressure Cardiovascular disease Cholesterol Chromatography Cricetinae Decomposition Dietary fiber Dietary Fiber - administration & dosage Flammulina - chemistry Flammulina velutipes Free radicals Fungal Polysaccharides - administration & dosage Hypolipidemic Agents - administration & dosage Lipid Metabolism - drug effects Lipid Metabolism - physiology Lipids Lipoproteins, HDL - blood Liver Male Mesocricetus Molecular weight Mushrooms Nutrition research Sterols - administration & dosage |
| title | Hypolipidemic and Antioxidant Activity of Enoki Mushrooms (Flammulina velutipes) |
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