Interleukin‐6 myokine signaling in skeletal muscle: a double‐edged sword?

Interleukin (IL)‐6 is a cytokine with pleiotropic functions in different tissues and organs. Skeletal muscle produces and releases significant levels of IL‐6 after prolonged exercise and is therefore considered as a myokine. Muscle is also an important target of the cytokine. IL‐6 signaling has been...

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Veröffentlicht in:	The FEBS journal 2013-09, Vol.280 (17), p.4131-4148
Hauptverfasser:	Muñoz‐Cánoves, Pura, Scheele, Camilla, Pedersen, Bente K., Serrano, Antonio L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cellular biology Creixement Cytokines Energy Metabolism Growth/atrophy Humans IL-6 Inflammation Interleukin-6 - metabolism Metabolism Muscle Development - physiology Muscle Fibrosis and Inflammation Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscular Atrophy - metabolism Muscular Atrophy - pathology Musculoskeletal system Myogenesis Myokine Músculs Pathway Regeneration Review Satellite cell Signal Transduction Signaling signaling pathway Skeletal muscle
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