Urinary Excretion of Neutrophil Gelatinase-Associated Lipocalin in Diabetic Rats

Recent studies suggest that tubular damage precedes glomerular damage in the progression of diabetic nephropathy. Therefore, we evaluated oxidative stress and urinary excretion of tubular proteins as markers of tubular dysfunction. Methods. Diabetes was induced in rats by streptozotocin administrati...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2014-01, Vol.2014 (2014), p.1-11
Hauptverfasser:	Osorio, Horacio, Tapia, Edilia, Loredo-Mendoza, María Lilia, Cristóbal-García, Magdalena, García-Arroyo, Fernando Enrique, Arellano, Abraham, Sánchez-Lozada, Laura Gabriela
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute-Phase Proteins - urine Animals Biomarkers Biomarkers - urine Cardiovascular disease Carrier proteins Development and progression Diabetes Diabetes Mellitus, Experimental - pathology Diabetes Mellitus, Experimental - urine Diabetic nephropathies Diabetic Nephropathies - pathology Diabetic Nephropathies - urine Federal regulation Health aspects Heart surgery Hyperglycemia Laboratories Lipocalins - urine Male Metabolism Neutrophils Oxidative stress Oxidative Stress - physiology Proteins Proto-Oncogene Proteins - urine Rats Rats, Wistar Reactive Oxygen Species - metabolism Rodents Studies Urine
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