Identification of molecular sub-networks associated with cell survival in a chronically SIVmac-infected human CD4+ T cell line

BACKGROUND: The deciphering of cellular networks to determine susceptibility to infection by HIV or the related simian immunodeficiency virus (SIV) is a major challenge in infection biology. RESULTS: Here, we have compared gene expression profiles of a human CD4⁺ T cell line at 24 h after infection...

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Veröffentlicht in:	Virology journal 2014-08, Vol.11 (1), p.152-152, Article 152
Hauptverfasser:	He, Feng Q, Sauermann, Ulrike, Beer, Christiane, Winkelmann, Silke, Yu, Zheng, Sopper, Sieghart, Zeng, An-Ping, Wirth, Manfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Caveolin 1 - genetics Caveolin 1 - metabolism CD4 Antigens - genetics CD4 Antigens - metabolism CD4-positive T-lymphocytes CD4-Positive T-Lymphocytes - virology Cell Cycle Cell death Cell Line Cell Proliferation Cell Survival cell viability Colleges & universities Comparative analysis Deoxyribonucleic acid Disease susceptibility DNA Enzymes Flow cytometry Gene expression Gene Expression Regulation Genes Genomes giant cells Health aspects HIV HIV infections HIV-1 Human immunodeficiency virus Humans Infections Kinases Lymphocytes Medical research Mobile communication systems Monkeys Physiological aspects prediction protein-protein interactions Proteins proviruses Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction signal transduction Simian immunodeficiency virus Simian Immunodeficiency Virus - physiology T cells Transcription factors Virus Attachment Virus diseases Virus Internalization Virus Replication - physiology Wireless communication systems
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