Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug ‘Patha’, and its other source plants by ISSR markers
Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman belongs to family Menispermaceae. The roots of this taxon are used in the treatment of various diseases like stomach pain, fever, skin disease, etc., in Ayurveda and is commonly known as Patha . Two other species, viz., Cyclea peltata (L...
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creator | Vijayan, Deepu Cheethaparambil, Archana Pillai, Geetha Sivadasan Balachandran, Indira |
description | Cissampelos pareira
L. var.
hirsuta
(Buch.-Ham. ex DC.) Forman belongs to family Menispermaceae. The roots of this taxon are used in the treatment of various diseases like stomach pain, fever, skin disease, etc., in Ayurveda and is commonly known as
Patha
. Two other species, viz.,
Cyclea peltata
(Lam.) Hook.f. & Thomson and
Stephania japonica
(Thunb.) Miers of the same family are being used as the source of this drug in various parts of India. This type of substitution or adulteration will ultimately affect the therapeutic efficacy of the medicines adversely. ISSR profiles of all the three taxa are generated and analyzed to assess the genetic relationships among these three species. The profiles of all the three species displayed a high level of polymorphism among them. ISSR markers developed can be used in authenticating and validating the exact species discrimination of the genuine raw drug of ‘
Patha
’ from its substitutes/adulterants to guarantee the quality and legitimacy of this drug in the market. |
doi_str_mv | 10.1007/s13205-013-0183-8 |
format | Article |
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L. var.
hirsuta
(Buch.-Ham. ex DC.) Forman belongs to family Menispermaceae. The roots of this taxon are used in the treatment of various diseases like stomach pain, fever, skin disease, etc., in Ayurveda and is commonly known as
Patha
. Two other species, viz.,
Cyclea peltata
(Lam.) Hook.f. & Thomson and
Stephania japonica
(Thunb.) Miers of the same family are being used as the source of this drug in various parts of India. This type of substitution or adulteration will ultimately affect the therapeutic efficacy of the medicines adversely. ISSR profiles of all the three taxa are generated and analyzed to assess the genetic relationships among these three species. The profiles of all the three species displayed a high level of polymorphism among them. ISSR markers developed can be used in authenticating and validating the exact species discrimination of the genuine raw drug of ‘
Patha
’ from its substitutes/adulterants to guarantee the quality and legitimacy of this drug in the market.</description><identifier>ISSN: 2190-572X</identifier><identifier>EISSN: 2190-5738</identifier><identifier>DOI: 10.1007/s13205-013-0183-8</identifier><identifier>PMID: 28324385</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adulterants ; adulterated products ; Agriculture ; Ayurvedic medicine ; Bioinformatics ; Biomaterials ; Biotechnology ; Cancer Research ; Chemistry ; Chemistry and Materials Science ; Cissampelos ; Cissampelos pareira ; Cyclea ; Fever ; genetic markers ; Genetic relationship ; genetic relationships ; herbal medicines ; India ; Markers ; markets ; Menispermaceae ; microsatellite repeats ; organisms ; Polymorphism ; roots ; Short Report ; Skin diseases ; Species ; Stem Cells ; Stephania japonica</subject><ispartof>3 Biotech, 2014-10, Vol.4 (5), p.559-562</ispartof><rights>The Author(s) 2013</rights><rights>The Author(s) 2013. This work is published under http://creativecommons.org/licenses/by/2.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-5e67656f88651ac774f93639e3a585f49b58b41b3a4c6ead01c6e97e744d107a3</citedby><cites>FETCH-LOGICAL-c503t-5e67656f88651ac774f93639e3a585f49b58b41b3a4c6ead01c6e97e744d107a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162895/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162895/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,41469,42538,51300,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28324385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vijayan, Deepu</creatorcontrib><creatorcontrib>Cheethaparambil, Archana</creatorcontrib><creatorcontrib>Pillai, Geetha Sivadasan</creatorcontrib><creatorcontrib>Balachandran, Indira</creatorcontrib><title>Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug ‘Patha’, and its other source plants by ISSR markers</title><title>3 Biotech</title><addtitle>3 Biotech</addtitle><addtitle>3 Biotech</addtitle><description>Cissampelos pareira
L. var.
hirsuta
(Buch.-Ham. ex DC.) Forman belongs to family Menispermaceae. The roots of this taxon are used in the treatment of various diseases like stomach pain, fever, skin disease, etc., in Ayurveda and is commonly known as
Patha
. Two other species, viz.,
Cyclea peltata
(Lam.) Hook.f. & Thomson and
Stephania japonica
(Thunb.) Miers of the same family are being used as the source of this drug in various parts of India. This type of substitution or adulteration will ultimately affect the therapeutic efficacy of the medicines adversely. ISSR profiles of all the three taxa are generated and analyzed to assess the genetic relationships among these three species. The profiles of all the three species displayed a high level of polymorphism among them. ISSR markers developed can be used in authenticating and validating the exact species discrimination of the genuine raw drug of ‘
Patha
’ from its substitutes/adulterants to guarantee the quality and legitimacy of this drug in the market.</description><subject>Adulterants</subject><subject>adulterated products</subject><subject>Agriculture</subject><subject>Ayurvedic medicine</subject><subject>Bioinformatics</subject><subject>Biomaterials</subject><subject>Biotechnology</subject><subject>Cancer Research</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Cissampelos</subject><subject>Cissampelos pareira</subject><subject>Cyclea</subject><subject>Fever</subject><subject>genetic markers</subject><subject>Genetic relationship</subject><subject>genetic relationships</subject><subject>herbal medicines</subject><subject>India</subject><subject>Markers</subject><subject>markets</subject><subject>Menispermaceae</subject><subject>microsatellite repeats</subject><subject>organisms</subject><subject>Polymorphism</subject><subject>roots</subject><subject>Short Report</subject><subject>Skin diseases</subject><subject>Species</subject><subject>Stem Cells</subject><subject>Stephania japonica</subject><issn>2190-572X</issn><issn>2190-5738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFUttu1DAQjRCIVqUfwAsaiZciNcGXOHFekMpCaaVFIAoSb9Zs4uy6JPFixwv71s-A7-FP-iV4tWWhSAhL1liaM2dmjk-SPKQko4SUTz3ljIiUUB6v5Km8k-wzWpFUlFze3b3Zx73k0PtLEo-goqLkfrLHJGc5l2I_-fHadroOHTrAMC70MJoaR2MHsC1MjPfYL3VnPSzRaeMQphms0GWwMM6HEeHoeagXWXqGfQb6K7yYZE_g1Loeh2OIfDDXQzCDBm-DqzUsOxzGDTeug1vpxtTg8As0Lszh-urbWxwXeH31_RhwaMCMHmwkcbeqPczWcH5x8Q56dJ-08w-Sey12Xh_exIPkw-nL95OzdPrm1fnkZJrWgvAxFbooC1G0UhaCYl2WeVvxgleao5CizauZkLOczjjmdaGxITSGqtRlnjeUlMgPkmdb3mWY9bqpo1gOO7V0Jg6yVhaNup0ZzELN7UrltGCyEpHg6IbA2c9B-1H1xte6i1tpG7xihBEphcyL_0KppPF_uazyCH38F_QyqjVEJRQrWBl7E8kjim5RtbPeO93u5qZEbQyltoZS0VBqYyglY82jPxfeVfyyTwSwLcDH1DDX7nfrf7P-BI--2G0</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Vijayan, Deepu</creator><creator>Cheethaparambil, Archana</creator><creator>Pillai, Geetha Sivadasan</creator><creator>Balachandran, Indira</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>L6V</scope><scope>LK8</scope><scope>M7P</scope><scope>M7S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope></search><sort><creationdate>20141001</creationdate><title>Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug ‘Patha’, and its other source plants by ISSR markers</title><author>Vijayan, Deepu ; Cheethaparambil, Archana ; Pillai, Geetha Sivadasan ; Balachandran, Indira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-5e67656f88651ac774f93639e3a585f49b58b41b3a4c6ead01c6e97e744d107a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adulterants</topic><topic>adulterated products</topic><topic>Agriculture</topic><topic>Ayurvedic medicine</topic><topic>Bioinformatics</topic><topic>Biomaterials</topic><topic>Biotechnology</topic><topic>Cancer Research</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Cissampelos</topic><topic>Cissampelos pareira</topic><topic>Cyclea</topic><topic>Fever</topic><topic>genetic markers</topic><topic>Genetic relationship</topic><topic>genetic relationships</topic><topic>herbal medicines</topic><topic>India</topic><topic>Markers</topic><topic>markets</topic><topic>Menispermaceae</topic><topic>microsatellite repeats</topic><topic>organisms</topic><topic>Polymorphism</topic><topic>roots</topic><topic>Short Report</topic><topic>Skin diseases</topic><topic>Species</topic><topic>Stem Cells</topic><topic>Stephania japonica</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vijayan, Deepu</creatorcontrib><creatorcontrib>Cheethaparambil, Archana</creatorcontrib><creatorcontrib>Pillai, Geetha Sivadasan</creatorcontrib><creatorcontrib>Balachandran, Indira</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>3 Biotech</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vijayan, Deepu</au><au>Cheethaparambil, Archana</au><au>Pillai, Geetha Sivadasan</au><au>Balachandran, Indira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug ‘Patha’, and its other source plants by ISSR markers</atitle><jtitle>3 Biotech</jtitle><stitle>3 Biotech</stitle><addtitle>3 Biotech</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>4</volume><issue>5</issue><spage>559</spage><epage>562</epage><pages>559-562</pages><issn>2190-572X</issn><eissn>2190-5738</eissn><abstract>Cissampelos pareira
L. var.
hirsuta
(Buch.-Ham. ex DC.) Forman belongs to family Menispermaceae. The roots of this taxon are used in the treatment of various diseases like stomach pain, fever, skin disease, etc., in Ayurveda and is commonly known as
Patha
. Two other species, viz.,
Cyclea peltata
(Lam.) Hook.f. & Thomson and
Stephania japonica
(Thunb.) Miers of the same family are being used as the source of this drug in various parts of India. This type of substitution or adulteration will ultimately affect the therapeutic efficacy of the medicines adversely. ISSR profiles of all the three taxa are generated and analyzed to assess the genetic relationships among these three species. The profiles of all the three species displayed a high level of polymorphism among them. ISSR markers developed can be used in authenticating and validating the exact species discrimination of the genuine raw drug of ‘
Patha
’ from its substitutes/adulterants to guarantee the quality and legitimacy of this drug in the market.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>28324385</pmid><doi>10.1007/s13205-013-0183-8</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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source | SpringerLink Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Adulterants adulterated products Agriculture Ayurvedic medicine Bioinformatics Biomaterials Biotechnology Cancer Research Chemistry Chemistry and Materials Science Cissampelos Cissampelos pareira Cyclea Fever genetic markers Genetic relationship genetic relationships herbal medicines India Markers markets Menispermaceae microsatellite repeats organisms Polymorphism roots Short Report Skin diseases Species Stem Cells Stephania japonica |
title | Molecular authentication of Cissampelos pareira L. var. hirsuta (Buch.-Ham. ex DC.) Forman, the genuine source plant of ayurvedic raw drug ‘Patha’, and its other source plants by ISSR markers |
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