GPC3 reduces cell proliferation in renal carcinoma cell lines

Glypican 3 (GPC3) is a member of the family of glypican heparan sulfate proteoglycans (HSPGs). The GPC3 gene may play a role in controlling cell migration, negatively regulating cell growth and inducing apoptosis. GPC3 is downregulated in several cancers, which can result in uncontrolled cell growth...

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Veröffentlicht in:	BMC cancer 2014-08, Vol.14 (1), p.631-631, Article 631
Hauptverfasser:	Valsechi, Marina Curado, Oliveira, Ana Beatriz Bortolozo, Conceição, André Luis Giacometti, Stuqui, Bruna, Candido, Natalia Maria, Provazzi, Paola Jocelan Scarin, de Araújo, Luiza Ferreira, Silva, Jr, Wilson Araújo, Calmon, Marilia de Freitas, Rahal, Paula
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Breast cancer Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - pathology Cell Cycle Cell growth Cell Line, Tumor Cell Proliferation Deoxyribonucleic acid DNA Extracellular matrix Female Gene expression Gene Expression Regulation, Neoplastic Genomics Glypicans - genetics Glypicans - metabolism Humans Kidney Neoplasms - genetics Kidney Neoplasms - metabolism Kidney Neoplasms - pathology Liver cancer Male Metastasis Middle Aged Polymerase chain reaction Real time Rodents Studies Tumors
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