Cancer Therapy Using Ultrahigh Hydrophobic Drug-Loaded Graphene Derivatives

This study aimed to demonstrate that curcumin (Cur)-containing graphene composites have high anticancer activity. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug Cur based on pH dependence. Different Cur-graphene composites were prepare...

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Veröffentlicht in:	Scientific reports 2014-09, Vol.4 (1), p.6314, Article 6314
Hauptverfasser:	Some, Surajit, Gwon, A-Ryeong, Hwang, Eunhee, Bahn, Ga-hee, Yoon, Yeoheung, Kim, Youngmin, Kim, Seol-Hee, Bak, Sora, Yang, Junghee, Jo, Dong-Gyu, Lee, Hyoyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	14/10 14/34 14/5 631/61/54/152 631/67/1059/153 631/67/2321 64/60 Animals Antineoplastic Agents Antitumor activity Berries Cancer Cancer therapies Cell death Cell Line, Tumor Cell Survival - drug effects Chemotherapy Curcumin Curcumin - therapeutic use Drug Carriers - therapeutic use Female Graphite - chemistry Graphite - therapeutic use HCT116 Cells Humanities and Social Sciences Humans Hydrophobic and Hydrophilic Interactions Hydrophobicity Mice Mice, Inbred BALB C Microscopy, Electrochemical, Scanning multidisciplinary Nanocomposites - therapeutic use Neoplasm Transplantation Neoplasms - drug therapy Oxygen pH effects Quantum dots Quantum Dots - therapeutic use Science Synergistic effect Transplantation, Heterologous
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