The effects of ultra low fluence rate single and repetitive photodynamic therapy on glioma spheroids

Background and Objective Achieving local control of gliomas with photodynamic therapy (PDT) requires the delivery of adequate light fluences to depths of 1–2 cm in the resection margin where the majority of local recurrences originate. This is clinically impractical with current single‐shot, intraop...

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Veröffentlicht in:	Lasers in surgery and medicine 2009-10, Vol.41 (8), p.578-584
Hauptverfasser:	Mathews, Marlon S., Angell-Petersen, Even, Sanchez, Rogelio, Sun, Chung-Ho, Vo, Van, Hirschberg, Henry, Madsen, Steen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-aminolevulinic acid Aminolevulinic Acid - administration & dosage Brain tumors Cell Culture Techniques Cell Survival - drug effects Cell Survival - radiation effects chronic PDT Confocal microscopy fluence fluence rate Glioma Glioma - pathology Glioma - therapy human glioma spheroids Humans Lasers Light effects malignant glioma Photochemotherapy - methods photodynamic therapy Photosensitizing Agents - administration & dosage repetitive PDT spheroids Spheroids, Cellular - drug effects Spheroids, Cellular - radiation effects Tumor Cells, Cultured
Online-Zugang:	Volltext
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