Microwave & Magnetic (M2) Proteomics Reveals CNS-Specific Protein Expression Waves that Precede Clinical Symptoms of Experimental Autoimmune Encephalomyelitis

Central nervous system-specific proteins (CSPs), transported across the damaged blood-brain-barrier (BBB) to cerebrospinal fluid (CSF) and blood (serum), might be promising diagnostic, prognostic and predictive protein biomarkers of disease in individual multiple sclerosis (MS) patients because they...

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Veröffentlicht in:	Scientific reports 2014-09, Vol.4 (1), p.6210-6210, Article 6210
Hauptverfasser:	Raphael, Itay, Mahesula, Swetha, Purkar, Anjali, Black, David, Catala, Alexis, Gelfond, Jonathon A. L., Forsthuber, Thomas G., Haskins, William E.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/21 631/1647/2067 639/638/11/872 692/53/2421 82/58 Animal tissues Animals Biomarkers Blood Blood-brain barrier Central nervous system Central Nervous System - metabolism Cerebrospinal fluid Disease Models, Animal Encephalomyelitis, Autoimmune, Experimental - metabolism Enzyme-linked immunosorbent assay Experimental allergic encephalomyelitis Female Humanities and Social Sciences Immunoassay Immunoassays Inflammation Magnetic Phenomena Mice Mice, Inbred C57BL Microwaves multidisciplinary Multiple sclerosis Multiple Sclerosis - metabolism Nervous system Proteome - metabolism Proteomics Proteomics - methods Science Spectrin Spectrin - metabolism Synapsin Synapsins - metabolism T cell receptors
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