Colonic inflammation and secondary bile acids in alcoholic cirrhosis

Alcohol abuse with/without cirrhosis is associated with an impaired gut barrier and inflammation. Gut microbiota can transform primary bile acids (BA) to secondary BAs, which can adversely impact the gut barrier. The purpose of this study was to define the effect of active alcohol intake on fecal BA...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2014-06, Vol.306 (11), p.G929-G937
Hauptverfasser:	Kakiyama, Genta, Hylemon, Phillip B, Zhou, Huiping, Pandak, William M, Heuman, Douglas M, Kang, Dae Joong, Takei, Hajime, Nittono, Hiroshi, Ridlon, Jason M, Fuchs, Michael, Gurley, Emily C, Wang, Yun, Liu, Runping, Sanyal, Arun J, Gillevet, Patrick M, Bajaj, Jasmohan S
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism - complications Bile Acids and Salts - chemistry Bile Acids and Salts - metabolism Call for Papers Colonic Diseases - chemically induced Colonic Diseases - pathology Feces - chemistry Humans Inflammation - etiology Inflammation - pathology Liver Cirrhosis - complications Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Middle Aged
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