Supression of chronic central pain by superoxide dismutase in rats with spinal cord injury: Inhibition of the NMDA receptor implicated

Superoxide dismutase (SOD) is used to manage chronic pain, including neuropathic and inflammatory pain. However, data regarding the clinical effectiveness are conflicting and the neurophysiological mechanism of SOD has yet to be elucidated. The aim of the present study was to investigate whether SOD...

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Veröffentlicht in:	Experimental and therapeutic medicine 2014-10, Vol.8 (4), p.1137-1141
Hauptverfasser:	XIE, YONG-GANG, MU, HONG-JIE, LI, ZHEN, MA, JIA-HAI, WANG, YUE-LAN
Format:	Artikel
Sprache:	eng
Schlagworte:	Behavior chronic central pain Chronic pain Drug therapy Gene expression Health aspects inhibition Neurons Pain phosphorylated N-methyl-D-aspartate receptor subunit 1 Phosphorylation Rodents Spinal cord injuries spinal cord injury Superoxide dismutase
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