Quantifying sequence and structural features of protein-RNA interactions

Increasing awareness of the importance of protein-RNA interactions has motivated many approaches to predict residue-level RNA binding sites in proteins based on sequence or structural characteristics. Sequence-based predictors are usually high in sensitivity but low in specificity; conversely struct...

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Veröffentlicht in:	Nucleic acids research 2014-09, Vol.42 (15), p.10086-10098
Hauptverfasser:	Li, Songling, Yamashita, Kazuo, Amada, Karlou Mar, Standley, Daron M
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Amino Acids - chemistry Artificial Intelligence Binding Sites Models, Molecular Protein Binding Protein Structure, Secondary RNA RNA - chemistry RNA - metabolism RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism Sequence Analysis, Protein Software Structural Homology, Protein
Online-Zugang:	Volltext
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