Rationally tuning the reduction potential of a single cupredoxin beyond the natural range

'Super' metalloproteins Many metalloproteins — proteins that contain metal atoms in their active sites — are crucial for biological reactions involving electron transfer. Marshall et al . now demonstrate that it is possible to tune the reduction potential of a single cupredoxin molecule —...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2009-11, Vol.462 (7269), p.113-116
Hauptverfasser:	Marshall, Nicholas M., Garner, Dewain K., Wilson, Tiffany D., Gao, Yi-Gui, Robinson, Howard, Nilges, Mark J., Lu, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	30 DIRECT ENERGY CONVERSION ADDITIVES Analytical, structural and metabolic biochemistry Aqueous solutions Azurin - chemistry Azurin - genetics Azurin - metabolism Bacterial proteins Binding Sites Biological and medical sciences BIOLOGY CATALYSIS Chemical properties CHEMISTRY Copper - metabolism Copper in the body Crystallography, X-Ray DESIGN ELECTROCATALYSTS ELECTRON TRANSFER Electron transport ENERGY CONVERSION FUEL CELLS Fuel technology Fundamental and applied biological sciences. Psychology Humanities and Social Sciences Hydrogen Bonding Hydrogen bonds Hydrophobic and Hydrophilic Interactions hydrophobicity letter Metalloproteins Metals Models, Molecular multidisciplinary Mutant Proteins - chemistry Mutant Proteins - genetics Mutant Proteins - metabolism Mutation national synchrotron light source NMR Nuclear magnetic resonance Other metalloproteins Oxidation-Reduction PHOTOSYNTHESIS Protein Conformation PROTEINS Q1 REDOX POTENTIAL RESPIRATION Science Science (multidisciplinary) TUNING
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!