Acceleration of Tissue Plasminogen Activator-Mediated Thrombolysis by Magnetically Powered Nanomotors

Dose control and effectiveness promotion of tissue plasminogen activator (t-PA) for thrombolysis are vitally important to alleviate serious side effects such as hemorrhage in stroke treatments. In order to increase the effectiveness and reduce the risk of stroke treatment, we use rotating magnetic n...

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Veröffentlicht in:	ACS nano 2014-08, Vol.8 (8), p.7746-7754
Hauptverfasser:	Cheng, Rui, Huang, Weijie, Huang, Lijie, Yang, Bo, Mao, Leidong, Jin, Kunlin, ZhuGe, Qichuan, Zhao, Yiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Diffusion Drug Delivery Systems - instrumentation Fibrin - metabolism Mice Mice, Inbred C57BL Nanotechnology - instrumentation Nanotubes Rotation Stroke - drug therapy Thrombosis - drug therapy Thrombosis - metabolism Time Factors Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - metabolism Tissue Plasminogen Activator - therapeutic use
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