Neuroprotective effect of heme oxygenase-2 knockout in the blood injection model of intracerebral hemorrhage

The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme oxygenase-2 (HO-2), the constitutive isoform, protects neurons from hemin in vitro and reduc...

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Veröffentlicht in:	BMC research notes 2014-08, Vol.7 (1), p.561, Article 561
Hauptverfasser:	Chen-Roetling, Jing, Cai, Ying, Regan, Raymond F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Care and treatment Cerebral Hemorrhage - enzymology Cerebral Hemorrhage - genetics Diagnosis Enzymes Experiments Health aspects Heme Oxygenase (Decyclizing) - genetics Intracerebral hemorrhage Mice Mice, Knockout Neurons Risk factors Rodents Short Report Studies
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