Molecular Imaging with Bioluminescence and PET Reveals Viral Oncolysis Kinetics and Tumor Viability

Viral oncolysis, the destruction of cancer cells by replicating virus, is an experimental cancer therapy that continues to be explored. The treatment paradigm for this therapy involves successive waves of lytic replication in cancer cells. At present, monitoring viral titer at sites of replication r...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2014-08, Vol.74 (15), p.4111-4121
Hauptverfasser:	KURUPPU, Darshini, BROWNELL, Anna-Liisa, SHAH, Khalid, MAHMOOD, Umar, TANABE, Kenneth K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Breast Neoplasms - therapy Breast Neoplasms - virology Cell Line, Tumor Cercopithecus aethiops Colonic Neoplasms - diagnostic imaging Colonic Neoplasms - pathology Colonic Neoplasms - therapy Colonic Neoplasms - virology Female HT29 Cells Humans Luminescent Measurements - methods Medical sciences Melanoma, Amelanotic - diagnostic imaging Melanoma, Amelanotic - pathology Melanoma, Amelanotic - therapy Melanoma, Amelanotic - virology Mice Mice, Inbred BALB C Mice, Nude Molecular Imaging - methods Oncolytic Virotherapy - methods Oncolytic Viruses - physiology Other treatments Pharmacology. Drug treatments Positron-Emission Tomography - methods Treatment. General aspects Tumors Vero Cells
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