Decreased fragile histidine triad expression in colorectal cancer and its association with apoptosis inhibition

AIM： To detect the expression of fragile histidine triad （FHIT） in normal colorectal tissue, colorectal adenoma and colorectal cancer （CRC） tissue, and to analyze its relationship with the clinicopathological features of CRC, and apoptosis-associatecl proteins （Bcl-2, Bax, survivin） and apoptosis in...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2007-02, Vol.13 (7), p.1018-1026
Hauptverfasser:	Cao, Jie, Chen, Xiao-Ping, Li, Wang-Lin, Xia, Jie, Du, Hong, Tang, Wei-Biao, Wang, Hui, Chen, Xi-Wen, Xiao, Huan-Qing, Li, Yu-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Anhydride Hydrolases - genetics Acid Anhydride Hydrolases - metabolism Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenoma - genetics Adenoma - metabolism Adenoma - pathology Adult Aged Aged, 80 and over Apoptosis - physiology bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - metabolism Colorectal Cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Female Gene Expression Regulation, Neoplastic - physiology Humans Inhibitor of Apoptosis Proteins Male Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Middle Aged Mutation - genetics Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Survivin 直肠癌组氨酸细胞凋亡结肠癌
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