Localization of Sarcomeric Proteins During Myofibril Assembly in Cultured Mouse Primary Skeletal Myotubes

ABSTRACT It is important to understand how muscle forms normally in order to understand muscle diseases that result in abnormal muscle formation. Although the structure of myofibrils is well understood, the process through which the myofibril components form organized contractile units is not clear....

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Veröffentlicht in:	Anatomical record (Hoboken, N.J. : 2007) N.J. : 2007), 2014-09, Vol.297 (9), p.1571-1584
Hauptverfasser:	White, Jennifer, Barro, Marietta V., Makarenkova, Helen P., Sanger, Joseph W., Sanger, Jean M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinin - metabolism Actins - metabolism Animals Cell Line Connectin - metabolism Mice Muscle Development Muscle Fibers, Skeletal - metabolism Muscle Fibers, Skeletal - physiology Muscle Proteins - metabolism myofibrillogenesis Myofibrils - metabolism Myofibrils - physiology nonmuscle myosin II Nonmuscle Myosin Type IIA - metabolism Nonmuscle Myosin Type IIB - metabolism premyofibrils Primary Cell Culture Sarcomeres - metabolism Sarcomeres - physiology telethonin α‐actinin
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