miR-375 Suppresses IGF1R Expression and Contributes to Inhibition of Cell Progression in Laryngeal Squamous Cell Carcinoma

MicroRNAs (miRNAs) are small noncoding RNA molecules which are involved in tumorigenesis and development. To investigate their role in primary laryngeal squamous cell carcinoma (LSCC), miRNA GeneChips were used to screen the differentially expressed miRNA, and then validated by real-time quantitativ...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-11
Hauptverfasser:	Luo, Jie, Wu, Jianhui, Li, John Zeng Hong, Qin, Hao, Wang, Bin, Wong, Thian-Sze, Yang, Weiqiang, Fu, Qing-Ling, Lei, Wenbin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Binding sites Biomedical research Cancer Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Cell growth Cell Line, Tumor Cell Proliferation - genetics Cell Transformation, Neoplastic - genetics Development and progression Gene expression Gene Expression Regulation, Neoplastic Humans Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Kinases Laryngeal cancer Laryngeal Neoplasms - genetics Laryngeal Neoplasms - pathology MicroRNA MicroRNAs - genetics MicroRNAs - metabolism Migration Oncogene Protein v-akt - biosynthesis Otolaryngology Physiological aspects Proteins Receptors, Somatomedin - biosynthesis Signal Transduction Squamous cell carcinoma Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!