Buccal microRNA dysregulation in lung field carcinogenesis: Gender-specific implications

MicroRNAs (miRNAs) have been shown to be reliable early biomarkers in a variety of cancers including that of lung. We ascertained whether the biomarker potential of miRNAs could be validated in microscopically normal and easily accessible buccal epithelial brushings from cigarette smokers as a conse...

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Veröffentlicht in:	International journal of oncology 2014-09, Vol.45 (3), p.1209-1215
Hauptverfasser:	WALI, RAMESH K, HENSING, THOMAS A, RAY, DANIEL W, DELA CRUZ, MART, TIWARI, ASHISH K, RADOSEVICH, ANDREW, JEPEAL, LISA, FERNANDO, HIRAN C, LITLE, VIRGINIA R, CHARLOT, MARJORY, MOMI, NAVNEET, BACKMAN, VADIM, ROY, HEMANT K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged biomarker Biomarkers Biomarkers, Tumor - genetics buccal mucosa Carcinogenesis Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Case-Control Studies Cellular biology Chronic obstructive pulmonary disease Cigarettes Demographics Early Detection of Cancer - methods Female Gender Gene expression Gene Expression Regulation, Neoplastic human lung cancer Humans Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Male Males Medical prognosis Medical screening MicroRNA MicroRNAs MicroRNAs - genetics Middle Aged Mouth Mucosa - metabolism Sex Characteristics Smoking Smoking - genetics Smoking - pathology Software Studies
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