Patient-reported outcomes in the practice-based opportunities for weight reduction (POWER) trial
Purpose To evaluate effects of two behavioral weight-loss interventions (in-person, remote) on health-related quality of life (HRQOL) compared to a control intervention. Methods Four hundred and fifty-one obese US adults with at least one cardiovascular risk factor completed five measures of HRQOL a...
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| Veröffentlicht in: | Quality of life research 2013-11, Vol.22 (9), p.2389-2398 |
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| creator | Rubin, R. R. Peyrot, M. Wang, N.-Y. Coughlin, J. W. Jerome, G. J. Fitzpatrick, S. L. Bennett, W. L. Dalcin, A. Daumit, G. Durkin, N. Chang, Y.-T. Yeh, H.-C. Louis, T. A. Appel, L. J. |
| description | Purpose To evaluate effects of two behavioral weight-loss interventions (in-person, remote) on health-related quality of life (HRQOL) compared to a control intervention. Methods Four hundred and fifty-one obese US adults with at least one cardiovascular risk factor completed five measures of HRQOL and depression: MOS SF-12 physical component summary (PCS) and mental component summary; EuroQoL-5 dimensions single index and visual analog scale; PHQ-8 depression symptoms; and PSQI sleep quality scores at baseline and 6 and 24 months after randomization. Change in each outcome was analyzed using outcome-specific mixed-effects models controlling for participant demographic characteristics. Results PCS-12 scores over 24 months improved more among participants in the in-person active intervention arm than among control arm participants (P < 0.05, ES = 0.21); there were no other statistically significant treatment arm differences in HRQOL change. Greater weight loss was associated with improvements in most outcomes (P < 0.05 to < 0.0001). Conclusions Participants in the in-person active intervention improved more in physical function HRQOL than participants in the control arm did. Greater weight loss during the study was associated with greater improvement in all PRO except for sleep quality, suggesting that weight loss is a key factor in improving HRQOL. |
| doi_str_mv | 10.1007/s11136-013-0363-3 |
| format | Article |
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R. ; Peyrot, M. ; Wang, N.-Y. ; Coughlin, J. W. ; Jerome, G. J. ; Fitzpatrick, S. L. ; Bennett, W. L. ; Dalcin, A. ; Daumit, G. ; Durkin, N. ; Chang, Y.-T. ; Yeh, H.-C. ; Louis, T. A. ; Appel, L. J.</creator><creatorcontrib>Rubin, R. R. ; Peyrot, M. ; Wang, N.-Y. ; Coughlin, J. W. ; Jerome, G. J. ; Fitzpatrick, S. L. ; Bennett, W. L. ; Dalcin, A. ; Daumit, G. ; Durkin, N. ; Chang, Y.-T. ; Yeh, H.-C. ; Louis, T. A. ; Appel, L. J.</creatorcontrib><description>Purpose To evaluate effects of two behavioral weight-loss interventions (in-person, remote) on health-related quality of life (HRQOL) compared to a control intervention. Methods Four hundred and fifty-one obese US adults with at least one cardiovascular risk factor completed five measures of HRQOL and depression: MOS SF-12 physical component summary (PCS) and mental component summary; EuroQoL-5 dimensions single index and visual analog scale; PHQ-8 depression symptoms; and PSQI sleep quality scores at baseline and 6 and 24 months after randomization. Change in each outcome was analyzed using outcome-specific mixed-effects models controlling for participant demographic characteristics. Results PCS-12 scores over 24 months improved more among participants in the in-person active intervention arm than among control arm participants (P < 0.05, ES = 0.21); there were no other statistically significant treatment arm differences in HRQOL change. Greater weight loss was associated with improvements in most outcomes (P < 0.05 to < 0.0001). Conclusions Participants in the in-person active intervention improved more in physical function HRQOL than participants in the control arm did. Greater weight loss during the study was associated with greater improvement in all PRO except for sleep quality, suggesting that weight loss is a key factor in improving HRQOL.</description><identifier>ISSN: 0962-9343</identifier><identifier>EISSN: 1573-2649</identifier><identifier>DOI: 10.1007/s11136-013-0363-3</identifier><identifier>PMID: 23515902</identifier><language>eng</language><publisher>Dordrecht: Springer</publisher><subject>Adult ; Behavior Therapy ; Body mass index ; Clinical outcomes ; Data collection ; Depression ; Depressive disorders ; Diabetes ; Epidemiology ; Experimentation ; Female ; Health Status ; Humans ; Internet ; Intervention ; Male ; Medical practices ; Medicine ; Medicine & Public Health ; Mental depression ; Middle Aged ; Mortality ; Obesity ; Obesity - physiopathology ; Obesity - psychology ; Obesity - therapy ; P values ; Pain Measurement ; Patients ; Primary care ; Psychoeducational intervention ; Public Health ; Quality of Life ; Quality of Life Research ; Sleep ; Sleep Wake Disorders ; Sociology ; Treatment Outcome ; Type 2 diabetes mellitus ; Websites ; Weight control ; Weight Loss</subject><ispartof>Quality of life research, 2013-11, Vol.22 (9), p.2389-2398</ispartof><rights>Springer Science+Business Media Dordrecht 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-9a0377a30d7afb235ee526c5c2e4bda6049541c344f95579cd6652b9e8a17abe3</citedby><cites>FETCH-LOGICAL-c525t-9a0377a30d7afb235ee526c5c2e4bda6049541c344f95579cd6652b9e8a17abe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/24725462$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/24725462$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,776,780,799,881,27901,27902,41464,42533,51294,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23515902$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rubin, R. R.</creatorcontrib><creatorcontrib>Peyrot, M.</creatorcontrib><creatorcontrib>Wang, N.-Y.</creatorcontrib><creatorcontrib>Coughlin, J. W.</creatorcontrib><creatorcontrib>Jerome, G. J.</creatorcontrib><creatorcontrib>Fitzpatrick, S. L.</creatorcontrib><creatorcontrib>Bennett, W. L.</creatorcontrib><creatorcontrib>Dalcin, A.</creatorcontrib><creatorcontrib>Daumit, G.</creatorcontrib><creatorcontrib>Durkin, N.</creatorcontrib><creatorcontrib>Chang, Y.-T.</creatorcontrib><creatorcontrib>Yeh, H.-C.</creatorcontrib><creatorcontrib>Louis, T. A.</creatorcontrib><creatorcontrib>Appel, L. J.</creatorcontrib><title>Patient-reported outcomes in the practice-based opportunities for weight reduction (POWER) trial</title><title>Quality of life research</title><addtitle>Qual Life Res</addtitle><addtitle>Qual Life Res</addtitle><description>Purpose To evaluate effects of two behavioral weight-loss interventions (in-person, remote) on health-related quality of life (HRQOL) compared to a control intervention. Methods Four hundred and fifty-one obese US adults with at least one cardiovascular risk factor completed five measures of HRQOL and depression: MOS SF-12 physical component summary (PCS) and mental component summary; EuroQoL-5 dimensions single index and visual analog scale; PHQ-8 depression symptoms; and PSQI sleep quality scores at baseline and 6 and 24 months after randomization. Change in each outcome was analyzed using outcome-specific mixed-effects models controlling for participant demographic characteristics. Results PCS-12 scores over 24 months improved more among participants in the in-person active intervention arm than among control arm participants (P < 0.05, ES = 0.21); there were no other statistically significant treatment arm differences in HRQOL change. Greater weight loss was associated with improvements in most outcomes (P < 0.05 to < 0.0001). Conclusions Participants in the in-person active intervention improved more in physical function HRQOL than participants in the control arm did. Greater weight loss during the study was associated with greater improvement in all PRO except for sleep quality, suggesting that weight loss is a key factor in improving HRQOL.</description><subject>Adult</subject><subject>Behavior Therapy</subject><subject>Body mass index</subject><subject>Clinical outcomes</subject><subject>Data collection</subject><subject>Depression</subject><subject>Depressive disorders</subject><subject>Diabetes</subject><subject>Epidemiology</subject><subject>Experimentation</subject><subject>Female</subject><subject>Health Status</subject><subject>Humans</subject><subject>Internet</subject><subject>Intervention</subject><subject>Male</subject><subject>Medical practices</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Obesity</subject><subject>Obesity - physiopathology</subject><subject>Obesity - psychology</subject><subject>Obesity - therapy</subject><subject>P values</subject><subject>Pain Measurement</subject><subject>Patients</subject><subject>Primary care</subject><subject>Psychoeducational intervention</subject><subject>Public Health</subject><subject>Quality of Life</subject><subject>Quality of Life Research</subject><subject>Sleep</subject><subject>Sleep Wake Disorders</subject><subject>Sociology</subject><subject>Treatment Outcome</subject><subject>Type 2 diabetes mellitus</subject><subject>Websites</subject><subject>Weight control</subject><subject>Weight Loss</subject><issn>0962-9343</issn><issn>1573-2649</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU9rFTEUxYMo9ln9AC6UATftYjT_M9kIUmoVCi2iuIyZzJ338pg3GZOM4rc3w9RaXYgQSOD-zrn35iD0lOCXBGP1KhFCmKwxYTVmktXsHtoQoVhNJdf30QZrSWvNODtCj1LaY4wbjelDdESZIKI8N-jLtc0exlxHmELM0FVhzi4cIFV-rPIOqilal72DurVpKU8LN4--yFLVh1h9B7_d5SpCNxcwjNXJ9dXn8w-nVY7eDo_Rg94OCZ7c3Mfo09vzj2fv6suri_dnby5rJ6jItbaYKWUZ7pTt2zIfgKDSCUeBt52VmGvBiWOc91oIpV0npaCthsYSZVtgx-j16jvN7QE6V3aKdjBT9Acbf5hgvfmzMvqd2YZvhhOmGimKwcmNQQxfZ0jZHHxyMAx2hDAnQ4SgTEnO_gPlUjRCC00L-uIvdB_mOJafKIYlhWY5hSIr5WJIKUJ_OzfBZonarFGbErVZojasaJ7fXfhW8SvbAtAVSKU0biHeaf0P12eraJ9yiL9NuaKCS8p-ArnPvgE</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>Rubin, R. 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R. ; Peyrot, M. ; Wang, N.-Y. ; Coughlin, J. W. ; Jerome, G. J. ; Fitzpatrick, S. L. ; Bennett, W. L. ; Dalcin, A. ; Daumit, G. ; Durkin, N. ; Chang, Y.-T. ; Yeh, H.-C. ; Louis, T. A. ; Appel, L. 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R.</creatorcontrib><creatorcontrib>Peyrot, M.</creatorcontrib><creatorcontrib>Wang, N.-Y.</creatorcontrib><creatorcontrib>Coughlin, J. W.</creatorcontrib><creatorcontrib>Jerome, G. J.</creatorcontrib><creatorcontrib>Fitzpatrick, S. L.</creatorcontrib><creatorcontrib>Bennett, W. L.</creatorcontrib><creatorcontrib>Dalcin, A.</creatorcontrib><creatorcontrib>Daumit, G.</creatorcontrib><creatorcontrib>Durkin, N.</creatorcontrib><creatorcontrib>Chang, Y.-T.</creatorcontrib><creatorcontrib>Yeh, H.-C.</creatorcontrib><creatorcontrib>Louis, T. A.</creatorcontrib><creatorcontrib>Appel, L. 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R.</au><au>Peyrot, M.</au><au>Wang, N.-Y.</au><au>Coughlin, J. W.</au><au>Jerome, G. J.</au><au>Fitzpatrick, S. L.</au><au>Bennett, W. L.</au><au>Dalcin, A.</au><au>Daumit, G.</au><au>Durkin, N.</au><au>Chang, Y.-T.</au><au>Yeh, H.-C.</au><au>Louis, T. A.</au><au>Appel, L. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Patient-reported outcomes in the practice-based opportunities for weight reduction (POWER) trial</atitle><jtitle>Quality of life research</jtitle><stitle>Qual Life Res</stitle><addtitle>Qual Life Res</addtitle><date>2013-11-01</date><risdate>2013</risdate><volume>22</volume><issue>9</issue><spage>2389</spage><epage>2398</epage><pages>2389-2398</pages><issn>0962-9343</issn><eissn>1573-2649</eissn><abstract>Purpose To evaluate effects of two behavioral weight-loss interventions (in-person, remote) on health-related quality of life (HRQOL) compared to a control intervention. Methods Four hundred and fifty-one obese US adults with at least one cardiovascular risk factor completed five measures of HRQOL and depression: MOS SF-12 physical component summary (PCS) and mental component summary; EuroQoL-5 dimensions single index and visual analog scale; PHQ-8 depression symptoms; and PSQI sleep quality scores at baseline and 6 and 24 months after randomization. Change in each outcome was analyzed using outcome-specific mixed-effects models controlling for participant demographic characteristics. Results PCS-12 scores over 24 months improved more among participants in the in-person active intervention arm than among control arm participants (P < 0.05, ES = 0.21); there were no other statistically significant treatment arm differences in HRQOL change. Greater weight loss was associated with improvements in most outcomes (P < 0.05 to < 0.0001). Conclusions Participants in the in-person active intervention improved more in physical function HRQOL than participants in the control arm did. Greater weight loss during the study was associated with greater improvement in all PRO except for sleep quality, suggesting that weight loss is a key factor in improving HRQOL.</abstract><cop>Dordrecht</cop><pub>Springer</pub><pmid>23515902</pmid><doi>10.1007/s11136-013-0363-3</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Quality of life research, 2013-11, Vol.22 (9), p.2389-2398 |
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| source | Jstor Complete Legacy; MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Behavior Therapy Body mass index Clinical outcomes Data collection Depression Depressive disorders Diabetes Epidemiology Experimentation Female Health Status Humans Internet Intervention Male Medical practices Medicine Medicine & Public Health Mental depression Middle Aged Mortality Obesity Obesity - physiopathology Obesity - psychology Obesity - therapy P values Pain Measurement Patients Primary care Psychoeducational intervention Public Health Quality of Life Quality of Life Research Sleep Sleep Wake Disorders Sociology Treatment Outcome Type 2 diabetes mellitus Websites Weight control Weight Loss |
| title | Patient-reported outcomes in the practice-based opportunities for weight reduction (POWER) trial |
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