Impaired cytokine responses in patients with cryopyrin‐associated periodic syndrome (CAPS)

Summary Cryopyrin‐associated periodic syndrome (CAPS) is characterized by dysregulated inflammation with excessive interleukin (IL)‐1β activation and secretion. Neonatal‐onset multi‐system inflammatory disease (NOMID) is the most severe form. We explored cytokine responses in 32 CAPS patients before...

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Veröffentlicht in:	Clinical and experimental immunology 2014-09, Vol.177 (3), p.720-731
Hauptverfasser:	Haverkamp, M. H., Vosse, E., Goldbach‐Mansky, R., Holland, S. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anakinra Beta CAPS Carrier Proteins - genetics Child Child, Preschool Cryopyrin-Associated Periodic Syndromes - drug therapy Cryopyrin-Associated Periodic Syndromes - genetics Cryopyrin-Associated Periodic Syndromes - metabolism cytokine Cytokines Cytokines - metabolism Humans Immune system Infant Interleukin-1beta - antagonists & inhibitors Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Medical research Middle Aged Mutation - genetics NLR Family, Pyrin Domain-Containing 3 Protein NOMID Original Young Adult
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