Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity

Human rhinovirus (HRV) infections trigger exacerbations of lower airway diseases. HRV infects human airway epithelial cells and induces proinflammatory and antiviral molecules that regulate the response to HRV infection. Interferon (IFN)-stimulated gene of 15 kDa (ISG15) has been shown to regulate o...

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Veröffentlicht in:	Mucosal immunology 2014-09, Vol.7 (5), p.1127-1138
Hauptverfasser:	Zaheer, R S, Wiehler, S, Hudy, M H, Traves, S L, Pelikan, J B, Leigh, R, Proud, D
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/255/2514 631/250/262 631/326/596/2553 Adult Aged Allergology Antibodies Biomedical and Life Sciences Biomedicine Cell Line Cytokines - genetics Cytokines - immunology Epithelial Cells - immunology Epithelial Cells - virology Female Gastroenterology Gene Expression Regulation - immunology Humans Immunology Male Middle Aged Picornaviridae Infections - immunology Respiratory System - immunology Rhinovirus - immunology Time Factors Ubiquitins - genetics Ubiquitins - immunology Young Adult
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