Activation of ternary complex factor Elk‐1 by MAP kinases

Ternary complex factors (TCFs), one of which is Elk‐1, have been implicated in mediation of c‐fos induction. They have been shown to be phosphorylated by mitogen‐activated protein kinases (MAPKs) in vitro. We demonstrate that recombinant Elk‐1 is hyperphosphorylated in vivo upon joint overexpression...

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Veröffentlicht in:	The EMBO journal 1993-12, Vol.12 (13), p.5097-5104
Hauptverfasser:	Janknecht, R., Ernst, W.H., Pingoud, V., Nordheim, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell physiology DNA-Binding Proteins Enzyme Activation ets-Domain Protein Elk-1 Fundamental and applied biological sciences. Psychology Gene Expression Regulation Humans In Vitro Techniques Molecular and cellular biology Peptide Fragments - chemistry Phosphorylation Proto-Oncogene Proteins Proto-Oncogene Proteins c-fos - genetics Rabbits Retroviridae Proteins, Oncogenic - chemistry Retroviridae Proteins, Oncogenic - metabolism Signal Transduction Transcription Factors - metabolism Transcription, Genetic Transcriptional Activation
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