Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6

Bovine papillomavirus 1 E6 interacts with two similar proteins that regulate cell attachment and cell migration called paxillin (PXN) and HIC-5 (also known as HIC5, ARA55, HIC-5, TSC-5, and TGFB1I1). Despite the similarity between HIC-5 and paxillin, paxillin is required for E6 to transform mouse em...

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Veröffentlicht in:	Journal of virology 2014-09, Vol.88 (17), p.9927-9933
Hauptverfasser:	Brimer, Nicole, Wade, Ramon, Vande Pol, Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bovine papillomavirus 1 Bovine papillomavirus 1 - physiology Cell Cycle Proteins - metabolism Cells, Cultured Focal Adhesion Kinase 1 - metabolism GTPase-Activating Proteins - metabolism Human papillomavirus Mice Oncogene Proteins, Viral - metabolism Paxillin - metabolism Protein Interaction Mapping Transformation and Oncogenesis
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