Functional domains of the Drosophila Engrailed protein

We have studied the transcriptional activity of the Drosophila homeodomain protein Engrailed (En) by using a transient expression assay employing Schneider L2 cells. En was found to very strongly repress promoters activated by a variety of different activator proteins. However, unlike another Drosop...

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Veröffentlicht in:	The EMBO journal 1993-07, Vol.12 (7), p.2723-2733
Hauptverfasser:	Han, K, Manley, J.L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence amino acid sequences Animals Binding Sites Biological and medical sciences DNA, Recombinant - metabolism DNA-binding domains DNA-binding proteins Drosophila Drosophila melanogaster Drosophila Proteins en protein Fundamental and applied biological sciences. Psychology Fungal Proteins gene expression genetic regulation Homeodomain Proteins inhibition Insect Hormones - chemistry Insect Hormones - genetics Molecular and cellular biology Molecular genetics Molecular Sequence Data mutants promoter regions repression domains Trans-Activators - physiology transcription (genetics) Transcription Factors - chemistry Transcription Factors - genetics Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing transcriptional activators
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