PPX, a novel protein serine/threonine phosphatase localized to centrosomes

The amino acid sequence of a novel mammalian protein phosphatase, termed PPX (and designated PPP4 in the human genome nomenclature), has been deduced from the cDNA and shown to be 65% identical to PP2A alpha and PP2A beta and 45% identical to PPI isoforms, the predicted molecular mass being 35 kDa....

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Veröffentlicht in:	The EMBO journal 1993-03, Vol.12 (3), p.987-996
Hauptverfasser:	Brewis, N.D., Street, A.J., Prescott, A.R., Cohen, P.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Baculoviridae Base Sequence Biological and medical sciences Cells, Cultured centrosomes DNA Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Humans Hydrolases Liver - enzymology localization man Microtubules - metabolism Molecular Sequence Data Moths phosphoprotein phosphatase Phosphoprotein Phosphatases - genetics Phosphoprotein Phosphatases - metabolism PPP4 protein PPX protein Rabbits RNA, Messenger - genetics Substrate Specificity Tumor Cells, Cultured
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