Structural Insight into the DNA-Binding Mode of the Primosomal Proteins PriA, PriB, and DnaT

Replication restart primosome is a complex dynamic system that is essential for bacterial survival. This system uses various proteins to reinitiate chromosomal DNA replication to maintain genetic integrity after DNA damage. The replication restart primosome in Escherichia coli is composed of PriA he...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-14
Hauptverfasser:	Huang, Yen-Hua, Huang, Cheng-Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Binding sites Cellular proteins Chromosomes, Bacterial - chemistry Chromosomes, Bacterial - genetics Chromosomes, Bacterial - metabolism Deoxyribonucleic acid DNA DNA Helicases - chemistry DNA Helicases - genetics DNA Helicases - metabolism DNA repair DNA replication DNA, Bacterial - chemistry DNA, Bacterial - genetics DNA, Bacterial - metabolism DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism DNA-ligand interactions E coli Escherichia coli Escherichia coli - chemistry Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - chemistry Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Genetic research Health aspects Properties Proteins Review Review Article Structure-Activity Relationship
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