Association between genetic polymorphisms of cytochrome P450 2C19 and the risk of cerebral ischemic stroke in Chinese

Cytochrome P450 (CYP) 2C19 is a very important drug metabolizing enzyme. Although the single nucleotide polymorphisms (SNPs) of CYP2C19 G681A and G636A have been suggested that they may increase the incidence of cardiovascular events, the relationship between SNPs in CYP2C19 and cerebral ischemic st...

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Veröffentlicht in:	BMC genetics 2014-07, Vol.15 (1), p.83-83, Article 83
Hauptverfasser:	Gu, Shuzhen, Sun, Yan, Han, Ruifa, Wang, Lin, Wang, Dongliang, Wang, Jizuo, Li, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aryl Hydrocarbon Hydroxylases - genetics Asian Continental Ancestry Group - genetics Brain Ischemia - genetics Cardiovascular disease Case-Control Studies Cytochrome P-450 CYP2C19 Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype Humans Male Medical research Middle Aged Multivariate Analysis NMR Nuclear magnetic resonance Polymorphism, Single Nucleotide Recurrence Risk Factors Sequence Analysis, DNA Stroke Stroke - genetics Studies
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