Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L

Caspase-2 represents the most conserved member of the caspase family, which exhibits features of both initiator and effector caspases. Using ribonucleoprotein (RNP)-immunoprecipitation assay, we identified the proapoptotic caspase-2L encoding mRNA as a novel target of the ubiquitous RNA-binding prot...

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Veröffentlicht in:Cell death & disease 2014-07, Vol.5 (7), p.e1321-e1321
Hauptverfasser: Winkler, C, Doller, A, Imre, G, Badawi, A, Schmid, T, Schulz, S, Steinmeyer, N, Pfeilschifter, J, Rajalingam, K, Eberhardt, W
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Sprache:eng
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