Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements

Reverse transcription-derived sequences account for at least half of the human genome. Although these retroelements are formidable motors of evolution, they can occasionally cause disease, and accordingly are inactivated during early embryogenesis through epigenetic mechanisms. In the mouse, at leas...

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Veröffentlicht in:	Genome research 2014-08, Vol.24 (8), p.1260-1270
Hauptverfasser:	Turelli, Priscilla, Castro-Diaz, Nathaly, Marzetta, Flavia, Kapopoulou, Adamandia, Raclot, Charlène, Duc, Julien, Tieng, Vannary, Quenneville, Simon, Trono, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	Alu Elements Animals Cell Line DNA Methylation Embryonic Stem Cells Endogenous Retroviruses - genetics Gene Expression Regulation Humans Mice Repressor Proteins - physiology Retrovirus Transcription, Genetic Tripartite Motif-Containing Protein 28
Online-Zugang:	Volltext
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