Redox- and Hypoxia-Responsive MRI Contrast Agents

The development of responsive or “smart” magnetic resonance imaging (MRI) contrast agents that can report specific biomarker or biological events has been the focus of MRI contrast agent research over the past 20 years. Among various biological hallmarks of interest, tissue redox and hypoxia are par...

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Veröffentlicht in:	ChemMedChem 2014-06, Vol.9 (6), p.1116-1129
Hauptverfasser:	Do, Quyen N., Ratnakar, James S., Kovács, Zoltán, Sherry, A. Dean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Contrast agents Contrast Media - chemistry Coordination Complexes - chemistry Humans Hypoxia imaging agents Ligands Magnetic Resonance Imaging Magnetics Metals - chemistry Neoplasms - diagnosis Neoplasms - diagnostic imaging NMR Nuclear magnetic resonance Oxidation-Reduction PARACEST Radiography redox chemistry
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