Polymorphisms in vitamin D–related genes and risk of uterine leiomyomata

Objective To investigate uterine leiomyomata (UL) incidence in relation to polymorphisms in genes involved in vitamin D metabolism and skin pigmentation. Rates of UL are 2–3 times higher in African Americans than in European Americans. Recent studies suggest that vitamin D deficiency is associated w...

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Veröffentlicht in:	Fertility and sterility 2014-08, Vol.102 (2), p.503-510.e1
Hauptverfasser:	Wise, Lauren A., Sc.D, Ruiz-Narváez, Edward A., Sc.D, Haddad, Stephen A., M.Sc, Rosenberg, Lynn, Sc.D, Palmer, Julie R., Sc.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Americans African Americans - genetics Agouti Signaling Protein - genetics Case-Control Studies Chi-Square Distribution Female Gene Frequency Genetic Predisposition to Disease genetics Humans Incidence Internal Medicine Leiomyoma - diagnosis Leiomyoma - ethnology Leiomyoma - genetics Leiomyoma - metabolism Logistic Models Middle Aged Obstetrics and Gynecology Odds Ratio Oxidoreductases Acting on CH-CH Group Donors - genetics Phenotype Polymorphism, Single Nucleotide Prospective studies Registries Risk Assessment Risk Factors Skin Pigmentation - genetics United States - epidemiology uterine neoplasms Uterine Neoplasms - diagnosis Uterine Neoplasms - ethnology Uterine Neoplasms - genetics Uterine Neoplasms - metabolism vitamin D Vitamin D - metabolism
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