Site-specific opening of the blood-brain barrier

The blood‐brain barrier (BBB) poses a significant impediment for the delivery of therapeutic drugs into the brain. This is particularly problematic for the treatment of malignant gliomas which are characterized by diffuse infiltration of tumor cells into normal brain where they are protected by a pa...

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Veröffentlicht in:	Journal of biophotonics 2010-06, Vol.3 (5-6), p.356-367
Hauptverfasser:	Madsen, Steen J., Hirschberg, Henry
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals blood-brain barrier Blood-Brain Barrier - diagnostic imaging Blood-Brain Barrier - drug effects Blood-Brain Barrier - physiology Capillary Permeability - drug effects Clostridium perfringens prototoxin Drug Delivery Systems focused ultrasound Humans malignant glioma Models, Neurological photochemical internalization Photochemotherapy photodynamic therapy targeted opening Therapeutics - methods Ultrasonic Therapy Ultrasonography
Online-Zugang:	Volltext
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