Progesterone protects blood-brain barrier function and improves neurological outcome following traumatic brain injury in rats

Inflammatory responses are associated with blood-brain barrier (BBB) dysfunction and neurological deficits following traumatic brain injury (TBI). The aim of the present study was to investigate the effects of progesterone on the expression of the inflammatory mediators prostaglandin E2 (PGE2), cycl...

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Veröffentlicht in:	Experimental and therapeutic medicine 2014-09, Vol.8 (3), p.1010-1014
Hauptverfasser:	SI, DAOWEN, LI, JUAN, LIU, JIANG, WANG, XIAOYIN, WEI, ZIFENG, TIAN, QINGYOU, WANG, HAITAO, LIU, GANG
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood-brain barrier Brain Dosage and administration Edema Inflammation Injuries Lipid peroxidation Lipids Metabolism neurological function Permeability Physiological aspects Progesterone Rodents Studies Trauma Traumatic brain injury Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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