Pharmacokinetic Comparison of Sustained-Release and Standard Buprenorphine in Mice

Effective pain medication is important for animal stewardship and valid research results. We compared the pharmacokinetic assessments of standard, immediate-release buprenorphine (Bup IR) and a sustained-release buprenorphine formulation (Bup SR Lab) in male C57BL/6J mice, a mouse strain commonly us...

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Veröffentlicht in:	Journal of the American Association for Laboratory Animal Science 2014-07, Vol.53 (4), p.387-391
Hauptverfasser:	Clark, Tannia S, Clark, David D, Hoyt, Robert F
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid - administration & dosage Analgesics, Opioid - pharmacokinetics Anesthesia Animals Buprenorphine - administration & dosage Buprenorphine - pharmacokinetics Delayed-Action Preparations Male Mice, Inbred C57BL Pain - drug therapy Pain Measurement
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