Long-term reduction of T-cell intracellular antigens leads to increased beta-actin expression

The permanent down-regulated expression of T-cell intracellular antigen (TIA) proteins in HeLa cells improves cytoskeleton-mediated functions such as cell proliferation and tumor growth. Making use of human and mouse cells with knocked down/out expression of T-cell intracellular antigen 1 (TIA1) and...

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Veröffentlicht in:	Molecular cancer 2014-04, Vol.13 (1), p.90-90, Article 90
Hauptverfasser:	Carrascoso, Isabel, Sánchez-Jiménez, Carmen, Izquierdo, José M
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Actins - genetics Actins - metabolism Analysis Animals Base Sequence Cell growth Fibroblasts - cytology Fibroblasts - metabolism Gene expression Gene Expression Regulation Genes, Reporter Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism HeLa Cells Humans Infection Messenger RNA Mice Molecular Sequence Data Physiological aspects Poly(A)-Binding Proteins - genetics Poly(A)-Binding Proteins - metabolism Polymerase chain reaction Protein expression Proteins RNA polymerase RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Signal Transduction Software T-Cell Intracellular Antigen-1
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