Novel roles for ATP-binding cassette G transporters in lipid redistribution in Toxoplasma

Toxoplasma is a protozoan parasite proficiently adapted to thrive in a parasitophorous vacuole (PV) formed in the cytoplasm of a large variety of mammalian cells. As an actively dividing organism, the parasite must adjust the lipid composition of its membranes to preserve organelle vitality and expa...

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Veröffentlicht in:	Molecular microbiology 2010-06, Vol.76 (5), p.1232-1249
Hauptverfasser:	Ehrenman, Karen, Sehgal, Alfica, Lige, Bao, Stedman, Timothy T, Joiner, Keith A, Coppens, Isabelle
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Amino Acid Sequence Animals ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Binding sites Biochemistry Biological and medical sciences Biological Transport - physiology Cell Membrane - chemistry Cell Membrane - metabolism Cercopithecus aethiops COS Cells Eukaryotes Fundamental and applied biological sciences. Psychology Host-Parasite Interactions Humans Lipid Metabolism Lipids Microbiology Molecular Sequence Data Organisms, Genetically Modified Parasitic protozoa Phospholipids - metabolism Plasma Protein Isoforms - genetics Protein Isoforms - metabolism Protozoan Proteins - genetics Protozoan Proteins - metabolism Sequence Alignment Sterols - metabolism Toxoplasma Toxoplasma - cytology Toxoplasma - genetics Toxoplasma - metabolism
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