Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E81

The glycoprotein milk fat globule-EGF factor 8 (MFG-E8) is expressed in several tissues and mediates diverse homeostatic functions. However, whether MFG-E8 plays a role in bone homeostasis has not been established. Here we show for the first time that osteoclasts express and are regulated by MFG-E8....

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Veröffentlicht in:The Journal of immunology (1950) 2014-06, Vol.193 (3), p.1383-1391
Hauptverfasser: Abe, Toshiharu, Shin, Jieun, Hosur, Kavita, Udey, Mark C., Chavakis, Triantafyllos, Hajishengallis, George
Format: Artikel
Sprache:eng
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