Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies

Human papillomavirus (HPV) is known to be associated with several types of human cancer, including cervical, vulvar, vaginal, penile, anal, and head-and-neck cancers. Among these cancers, HPV-associated head-and-neck cancers, inclusive of oropharyngeal squamous cell carcinoma (OSCC) and oral cavity...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of Dental Research 2014-07, Vol.93 (7_suppl), p.29S-36S
Hauptverfasser: Sathish, N., Wang, X., Yuan, Y.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 36S
container_issue 7_suppl
container_start_page 29S
container_title Journal of Dental Research
container_volume 93
creator Sathish, N.
Wang, X.
Yuan, Y.
description Human papillomavirus (HPV) is known to be associated with several types of human cancer, including cervical, vulvar, vaginal, penile, anal, and head-and-neck cancers. Among these cancers, HPV-associated head-and-neck cancers, inclusive of oropharyngeal squamous cell carcinoma (OSCC) and oral cavity squamous cell carcinomas (OCSCC), have recently risen dramatically in men under 50 years old. Within 20 years, the percentage of HPV-positive OSCC in total OSCC went from less than 20% to more than 70% in the United States and some European countries. This article reviews the incidence trend and pathogenesis of HPV-associated head-and-neck cancers as well as current treatment modalities for the disease.
doi_str_mv 10.1177/0022034514527969
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4107541</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0022034514527969</sage_id><sourcerecordid>2300612226</sourcerecordid><originalsourceid>FETCH-LOGICAL-c495t-260d3e03a8fcf9733f75cb1dd27cf98521dfda746dc19d33e2e3b58f75d4e6cd3</originalsourceid><addsrcrecordid>eNp1kUtLAzEUhYMotlb3rmTATV2M5j2TjSBFrVhoweo2pEmmTplHTWYK_ntTWqsWXIXL-e7JuRwAzhG8RihJbiDEGBLKEGU4EVwcgC5ilMaQCXQIums5XusdcOL9AkIkcEqOQQdTzglPSRc8D9tSVdFELfOiqEu1yl3ro_5w8nYVK-9rnavGmmjsVBENVKWt85GqTDR1VjWlrZropXEBmefWn4KjTBXenm3fHnh9uJ8OhvFo_Pg0uBvFmgrWxJhDQywkKs10JhJCsoTpGTIGJ2FOGUYmMyqh3GgkDCEWWzJjaaAMtVwb0gO3G99lOyut0SFFiCeXLi-V-5S1yuVfpcrf5bxeSYpgwigKBv2tgas_WusbWeZe26JQla1bLxFjiBNKhAjo5R66qFtXhfMkJhByhDHmgYIbSrvae2ezXRgE5bopud9UWLn4fcRu4buaAMQbwKu5_fn1X8MvGVGbMw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2300612226</pqid></control><display><type>article</type><title>Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies</title><source>MEDLINE</source><source>SAGE Complete A-Z List</source><source>Alma/SFX Local Collection</source><creator>Sathish, N. ; Wang, X. ; Yuan, Y.</creator><creatorcontrib>Sathish, N. ; Wang, X. ; Yuan, Y.</creatorcontrib><description>Human papillomavirus (HPV) is known to be associated with several types of human cancer, including cervical, vulvar, vaginal, penile, anal, and head-and-neck cancers. Among these cancers, HPV-associated head-and-neck cancers, inclusive of oropharyngeal squamous cell carcinoma (OSCC) and oral cavity squamous cell carcinomas (OCSCC), have recently risen dramatically in men under 50 years old. Within 20 years, the percentage of HPV-positive OSCC in total OSCC went from less than 20% to more than 70% in the United States and some European countries. This article reviews the incidence trend and pathogenesis of HPV-associated head-and-neck cancers as well as current treatment modalities for the disease.</description><identifier>ISSN: 0022-0345</identifier><identifier>ISSN: 1544-0591</identifier><identifier>EISSN: 1544-0591</identifier><identifier>DOI: 10.1177/0022034514527969</identifier><identifier>PMID: 24663683</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Alcohol ; Alphapapillomavirus - physiology ; Carcinoma, Squamous Cell - therapy ; Carcinoma, Squamous Cell - virology ; Cell Transformation, Viral - physiology ; Cervical cancer ; Clinical Reviews ; Etiology ; Head &amp; neck cancer ; Head and Neck Neoplasms - therapy ; Head and Neck Neoplasms - virology ; Human papillomavirus ; Humans ; Infections ; Investigations ; Medical prognosis ; Molecular Targeted Therapy ; Mouth Neoplasms - therapy ; Mouth Neoplasms - virology ; Neck ; Oral cancer ; Oral carcinoma ; Oral cavity ; Papillomavirus Infections - therapy ; Papillomavirus Infections - virology ; Pathogenesis ; Penis ; Squamous cell carcinoma ; Throat cancer ; Tobacco ; Vagina</subject><ispartof>Journal of Dental Research, 2014-07, Vol.93 (7_suppl), p.29S-36S</ispartof><rights>International &amp; American Associations for Dental Research</rights><rights>International &amp; American Associations for Dental Research.</rights><rights>International &amp; American Associations for Dental Research. 2014</rights><rights>International &amp; American Associations for Dental Research 2014 International &amp; American Associations for Dental Research</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-260d3e03a8fcf9733f75cb1dd27cf98521dfda746dc19d33e2e3b58f75d4e6cd3</citedby><cites>FETCH-LOGICAL-c495t-260d3e03a8fcf9733f75cb1dd27cf98521dfda746dc19d33e2e3b58f75d4e6cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0022034514527969$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0022034514527969$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>230,313,314,780,784,792,885,21819,27922,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24663683$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sathish, N.</creatorcontrib><creatorcontrib>Wang, X.</creatorcontrib><creatorcontrib>Yuan, Y.</creatorcontrib><title>Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies</title><title>Journal of Dental Research</title><addtitle>J Dent Res</addtitle><description>Human papillomavirus (HPV) is known to be associated with several types of human cancer, including cervical, vulvar, vaginal, penile, anal, and head-and-neck cancers. Among these cancers, HPV-associated head-and-neck cancers, inclusive of oropharyngeal squamous cell carcinoma (OSCC) and oral cavity squamous cell carcinomas (OCSCC), have recently risen dramatically in men under 50 years old. Within 20 years, the percentage of HPV-positive OSCC in total OSCC went from less than 20% to more than 70% in the United States and some European countries. This article reviews the incidence trend and pathogenesis of HPV-associated head-and-neck cancers as well as current treatment modalities for the disease.</description><subject>Alcohol</subject><subject>Alphapapillomavirus - physiology</subject><subject>Carcinoma, Squamous Cell - therapy</subject><subject>Carcinoma, Squamous Cell - virology</subject><subject>Cell Transformation, Viral - physiology</subject><subject>Cervical cancer</subject><subject>Clinical Reviews</subject><subject>Etiology</subject><subject>Head &amp; neck cancer</subject><subject>Head and Neck Neoplasms - therapy</subject><subject>Head and Neck Neoplasms - virology</subject><subject>Human papillomavirus</subject><subject>Humans</subject><subject>Infections</subject><subject>Investigations</subject><subject>Medical prognosis</subject><subject>Molecular Targeted Therapy</subject><subject>Mouth Neoplasms - therapy</subject><subject>Mouth Neoplasms - virology</subject><subject>Neck</subject><subject>Oral cancer</subject><subject>Oral carcinoma</subject><subject>Oral cavity</subject><subject>Papillomavirus Infections - therapy</subject><subject>Papillomavirus Infections - virology</subject><subject>Pathogenesis</subject><subject>Penis</subject><subject>Squamous cell carcinoma</subject><subject>Throat cancer</subject><subject>Tobacco</subject><subject>Vagina</subject><issn>0022-0345</issn><issn>1544-0591</issn><issn>1544-0591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUtLAzEUhYMotlb3rmTATV2M5j2TjSBFrVhoweo2pEmmTplHTWYK_ntTWqsWXIXL-e7JuRwAzhG8RihJbiDEGBLKEGU4EVwcgC5ilMaQCXQIums5XusdcOL9AkIkcEqOQQdTzglPSRc8D9tSVdFELfOiqEu1yl3ro_5w8nYVK-9rnavGmmjsVBENVKWt85GqTDR1VjWlrZropXEBmefWn4KjTBXenm3fHnh9uJ8OhvFo_Pg0uBvFmgrWxJhDQywkKs10JhJCsoTpGTIGJ2FOGUYmMyqh3GgkDCEWWzJjaaAMtVwb0gO3G99lOyut0SFFiCeXLi-V-5S1yuVfpcrf5bxeSYpgwigKBv2tgas_WusbWeZe26JQla1bLxFjiBNKhAjo5R66qFtXhfMkJhByhDHmgYIbSrvae2ezXRgE5bopud9UWLn4fcRu4buaAMQbwKu5_fn1X8MvGVGbMw</recordid><startdate>20140701</startdate><enddate>20140701</enddate><creator>Sathish, N.</creator><creator>Wang, X.</creator><creator>Yuan, Y.</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7U9</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20140701</creationdate><title>Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies</title><author>Sathish, N. ; Wang, X. ; Yuan, Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-260d3e03a8fcf9733f75cb1dd27cf98521dfda746dc19d33e2e3b58f75d4e6cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Alcohol</topic><topic>Alphapapillomavirus - physiology</topic><topic>Carcinoma, Squamous Cell - therapy</topic><topic>Carcinoma, Squamous Cell - virology</topic><topic>Cell Transformation, Viral - physiology</topic><topic>Cervical cancer</topic><topic>Clinical Reviews</topic><topic>Etiology</topic><topic>Head &amp; neck cancer</topic><topic>Head and Neck Neoplasms - therapy</topic><topic>Head and Neck Neoplasms - virology</topic><topic>Human papillomavirus</topic><topic>Humans</topic><topic>Infections</topic><topic>Investigations</topic><topic>Medical prognosis</topic><topic>Molecular Targeted Therapy</topic><topic>Mouth Neoplasms - therapy</topic><topic>Mouth Neoplasms - virology</topic><topic>Neck</topic><topic>Oral cancer</topic><topic>Oral carcinoma</topic><topic>Oral cavity</topic><topic>Papillomavirus Infections - therapy</topic><topic>Papillomavirus Infections - virology</topic><topic>Pathogenesis</topic><topic>Penis</topic><topic>Squamous cell carcinoma</topic><topic>Throat cancer</topic><topic>Tobacco</topic><topic>Vagina</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sathish, N.</creatorcontrib><creatorcontrib>Wang, X.</creatorcontrib><creatorcontrib>Yuan, Y.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Dental Research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sathish, N.</au><au>Wang, X.</au><au>Yuan, Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies</atitle><jtitle>Journal of Dental Research</jtitle><addtitle>J Dent Res</addtitle><date>2014-07-01</date><risdate>2014</risdate><volume>93</volume><issue>7_suppl</issue><spage>29S</spage><epage>36S</epage><pages>29S-36S</pages><issn>0022-0345</issn><issn>1544-0591</issn><eissn>1544-0591</eissn><abstract>Human papillomavirus (HPV) is known to be associated with several types of human cancer, including cervical, vulvar, vaginal, penile, anal, and head-and-neck cancers. Among these cancers, HPV-associated head-and-neck cancers, inclusive of oropharyngeal squamous cell carcinoma (OSCC) and oral cavity squamous cell carcinomas (OCSCC), have recently risen dramatically in men under 50 years old. Within 20 years, the percentage of HPV-positive OSCC in total OSCC went from less than 20% to more than 70% in the United States and some European countries. This article reviews the incidence trend and pathogenesis of HPV-associated head-and-neck cancers as well as current treatment modalities for the disease.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>24663683</pmid><doi>10.1177/0022034514527969</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0022-0345
ispartof Journal of Dental Research, 2014-07, Vol.93 (7_suppl), p.29S-36S
issn 0022-0345
1544-0591
1544-0591
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4107541
source MEDLINE; SAGE Complete A-Z List; Alma/SFX Local Collection
subjects Alcohol
Alphapapillomavirus - physiology
Carcinoma, Squamous Cell - therapy
Carcinoma, Squamous Cell - virology
Cell Transformation, Viral - physiology
Cervical cancer
Clinical Reviews
Etiology
Head & neck cancer
Head and Neck Neoplasms - therapy
Head and Neck Neoplasms - virology
Human papillomavirus
Humans
Infections
Investigations
Medical prognosis
Molecular Targeted Therapy
Mouth Neoplasms - therapy
Mouth Neoplasms - virology
Neck
Oral cancer
Oral carcinoma
Oral cavity
Papillomavirus Infections - therapy
Papillomavirus Infections - virology
Pathogenesis
Penis
Squamous cell carcinoma
Throat cancer
Tobacco
Vagina
title Human Papillomavirus (HPV)-associated Oral Cancers and Treatment Strategies
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T11%3A13%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Human%20Papillomavirus%20(HPV)-associated%20Oral%20Cancers%20and%20Treatment%20Strategies&rft.jtitle=Journal%20of%20Dental%20Research&rft.au=Sathish,%20N.&rft.date=2014-07-01&rft.volume=93&rft.issue=7_suppl&rft.spage=29S&rft.epage=36S&rft.pages=29S-36S&rft.issn=0022-0345&rft.eissn=1544-0591&rft_id=info:doi/10.1177/0022034514527969&rft_dat=%3Cproquest_pubme%3E2300612226%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2300612226&rft_id=info:pmid/24663683&rft_sage_id=10.1177_0022034514527969&rfr_iscdi=true