Efficient transduction of myeloid cells by a lentiviral vector that packages the Vpx accessory protein
Lentiviral vectors are widely used for the stable expression of genes and shRNA-mediated knockdown and are currently under development for clinical use in gene therapy. Pseudotyping of the vectors with VSV-G allows them to infect a wide range of cell-types. However, myeloid cells, such as dendritic...
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Veröffentlicht in: | Gene therapy 2012-08, Vol.20 (5), p.514-520 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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