Alendronate effect on the prevention of bone loss in early stages of ankylosing spondylitis : a randomized, double-blind, placebo-controlled pilot study

Ankylosing spondylitis (AS) is an inflammatory rheumatic disease that leads to a progressive ankylosis of vertebras and ossification of paravertebral ligaments. Bone loss and osteoporosis are amongst the important complications of AS, treatment of which is a challenging issue. Objectives: This study...

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