Genetic burden in multiple sclerosis families

A previous study using cumulative genetic risk estimations in multiple sclerosis (MS) successfully tracked the aggregation of susceptibility variants in multi-case and single-case families. It used a limited description of susceptibility loci available at the time (17 loci). Even though the full ros...

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Veröffentlicht in:	Genes and immunity 2013-10, Vol.14 (7), p.434-440
Hauptverfasser:	Isobe, N, Damotte, V, Lo Re, V, Ban, M, Pappas, D, Guillot-Noel, L, Rebeix, I, Compston, A, Mack, T, Cozen, W, Fontaine, B, Hauser, S L, Oksenberg, J R, Sawcer, S, Gourraud, P-A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/2489/144 631/250/249/1313/1666 Adult Analysis Biomedical and Life Sciences Biomedicine Cancer Research Case-Control Studies Data processing Disease Epigenetic inheritance Families & family life Female Gene Expression Genes Genetic aspects Genetic Load Genetic Loci Genetic Predisposition to Disease Genetic susceptibility Genetics Health risk assessment Human Genetics Humans Immunology Male Middle Aged Multiple sclerosis Multiple Sclerosis - genetics original-article Pedigree Polymorphism, Single Nucleotide Single-nucleotide polymorphism
Online-Zugang:	Volltext
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