Reversible nerve damage and corneal pathology in murine herpes simplex stromal keratitis

Herpes simplex virus type 1 (HSV-1) shedding from sensory neurons can trigger recurrent bouts of herpes stromal keratitis (HSK), an inflammatory response that leads to progressive corneal scarring and blindness. A mouse model of HSK is often used to delineate immunopathogenic mechanisms and bears ma...

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Veröffentlicht in:	Journal of virology 2014-07, Vol.88 (14), p.7870-7880
Hauptverfasser:	Yun, Hongmin, Rowe, Alexander M, Lathrop, Kira L, Harvey, Stephen A K, Hendricks, Robert L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blinking CD4-Positive T-Lymphocytes - immunology Cornea - pathology Disease Models, Animal Female Herpes simplex virus 1 Herpesvirus 1, Human - growth & development Keratitis, Herpetic - pathology Keratitis, Herpetic - virology Mice Mice, Inbred BALB C Pathogenesis and Immunity Peripheral Nerves - pathology
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