SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion

Group A streptococcus (GAS) is a human pathogen causing a wide repertoire of mild and severe diseases for which no vaccine is yet available. We recently reported the identification of three protein antigens that in combination conferred wide protection against GAS infection in mice. Here we focused...

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Veröffentlicht in:	Infection and immunity 2014-07, Vol.82 (7), p.2890-2901
Hauptverfasser:	Gallotta, Marilena, Gancitano, Giovanni, Pietrocola, Giampiero, Mora, Marirosa, Pezzicoli, Alfredo, Tuscano, Giovanna, Chiarot, Emiliano, Nardi-Dei, Vincenzo, Taddei, Anna Rita, Rindi, Simonetta, Speziale, Pietro, Soriani, Marco, Grandi, Guido, Margarit, Immaculada, Bensi, Giuliano
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Bacterial Bacteria Bacterial Adhesion - physiology Bacterial Proteins - genetics Bacterial Proteins - metabolism Cell Line Cloning, Molecular Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism Epithelial Cells - microbiology Gene Deletion Gene Expression Regulation, Bacterial - immunology Humans Lactococcus lactis Lactococcus lactis - metabolism Molecular Pathogenesis Protein Binding Streptococcus Streptococcus pyogenes Streptococcus pyogenes - cytology Streptococcus pyogenes - genetics Streptococcus pyogenes - metabolism
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