Two-Photon Neuronal and Astrocytic Stimulation with Azobenzene-Based Photoswitches

Synthetic photochromic compounds can be designed to control a variety of proteins and their biochemical functions in living cells, but the high spatiotemporal precision and tissue penetration of two-photon stimulation have never been investigated in these molecules. Here we demonstrate two-photon ex...

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Veröffentlicht in:	Journal of the American Chemical Society 2014-06, Vol.136 (24), p.8693-8701
Hauptverfasser:	Izquierdo-Serra, Mercè, Gascón-Moya, Marta, Hirtz, Jan J, Pittolo, Silvia, Poskanzer, Kira E, Ferrer, Èric, Alibés, Ramon, Busqué, Félix, Yuste, Rafael, Hernando, Jordi, Gorostiza, Pau
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Azo Compounds - chemical synthesis Azo Compounds - chemistry Biochemistry Cells, Cultured HEK293 Cells Humans Molecular Structure Neurons Photochemical Photochemical Processes Proteins Proteins - chemistry Protons Stimulation Strategy Switches
Online-Zugang:	Volltext
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