Therapeutically Targeting Neuroinflammation and Microglia after Acute Ischemic Stroke

Inflammation has a pivotal role in the pathogenesis of ischemic stroke, and recent studies posit that inflammation acts as a double-edged sword, not only detrimentally augmenting secondary injury, but also potentially promoting recovery. An initial event of inflammation in ischemic stroke is the act...

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Veröffentlicht in:	BioMed research international 2014-01, Vol.2014 (2014), p.1-9
Hauptverfasser:	Choi, Sung S., Lee, Youngjeon, Lee, Hong Jun, Chang, Kyu-Tae, Yeo, Hyeon-Gu, Lee, Sang-Rae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - chemistry Brain damage Brain Ischemia - therapy Care and treatment Cytokines Cytokines - metabolism Humans Immune system Inflammation Inflammation - therapy Inflammation Mediators - metabolism Microglia - pathology Phenotype Review Rodents Signal Transduction Stroke Stroke (Disease) Stroke - therapy
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