Population-specific common SNPs reflect demographic histories and highlight regions of genomic plasticity with functional relevance

Population differentiation is the result of demographic and evolutionary forces. Whole genome datasets from the 1000 Genomes Project (October 2012) provide an unbiased view of genetic variation across populations from Europe, Asia, Africa and the Americas. Common population-specific SNPs (MAF > 0...

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Veröffentlicht in:	BMC genomics 2014-06, Vol.15 (1), p.437-437, Article 437
Hauptverfasser:	Choudhury, Ananyo, Hazelhurst, Scott, Meintjes, Ayton, Achinike-Oduaran, Ovokeraye, Aron, Shaun, Gamieldien, Junaid, Jalali Sefid Dashti, Mahjoubeh, Mulder, Nicola, Tiffin, Nicki, Ramsay, Michèle
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Analysis Bioinformatics Computational Biology Databases, Nucleic Acid Disease Disease susceptibility Evolution, Molecular Genealogy Genes Genetic diversity Genetic engineering Genetics, Population Genome, Human Genomes Genomics Humans Mutation Ontology Polymorphism, Single Nucleotide Population Racial Groups - genetics Recombination, Genetic Selection, Genetic Single nucleotide polymorphisms Studies
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