Collagen triple helix repeat containing 1 is overexpressed in hepatocellular carcinoma and promotes cell proliferation and motility

Although several therapeutic options are available for hepatocellular carcinoma (HCC), the outcome is still very poor. One reason is the complexity of signal transduction in the pathogenesis of HCC. The aim of this study was to identify new HCC-related genes and to investigate the functions of these...

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Veröffentlicht in:	International journal of oncology 2014-08, Vol.45 (2), p.541-548
Hauptverfasser:	TAMEDA, MASAHIKO, SUGIMOTO, KAZUSHI, SHIRAKI, KATSUYA, YAMAMOTO, NORIHIKO, OKAMOTO, RYUJI, USUI, MASANOBU, ITO, MASAAKI, TAKEI, YOSHIYUKI, NOBORI, TSUTOMU, KOJIMA, TAKAHIRO, SUZUKI, HIDEAKI, UCHIDA, MASAKO, UCHIDA, KAZUHIKO
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers, Tumor - analysis Blotting, Western Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Cell adhesion & migration Cell growth Cell Movement - physiology Cell Proliferation - physiology Chromosomes collagen triple helix repeat containing 1 Comparative Genomic Hybridization copy number alteration Deoxyribonucleic acid Development and progression DNA DNA methylation Extracellular Matrix Proteins - biosynthesis Female Gene Dosage Gene expression Genetic aspects Genomes Growth factors Health aspects Hepatitis hepatocellular carcinoma Hepatoma Humans Immunohistochemistry Innovations integrin β Kinases Liver cancer Liver cirrhosis Liver Neoplasms - metabolism Liver Neoplasms - pathology Male Middle Aged Molecular targeted therapy Motility Pathogenesis Patients Proteins Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Rodents Signal transduction Transcriptome Up-Regulation
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